Basic information Safety Supplier Related

MKC8866

Basic information Safety Supplier Related

MKC8866 Basic information

Product Name:
MKC8866
Synonyms:
  • MKC8866
  • 2H-1-Benzopyran-8-carboxaldehyde, 7-hydroxy-6-methoxy-4-methyl-3-[2-(4-morpholinyl)-2-oxoethyl]-2-oxo-
  • IRE1 RNase inhibitor 8866 (MKC8866
  • 7-hydroxy-6-methoxy-4-methyl-3-(2-morpholino-2-oxoethyl)-2-oxo-2H-chromene-8-carbaldehyde
  • MKC8866;MKC-8866
  • 181697
  • IRE1 RNase inhibitor 8866
  • Inositol requiring enzyme 1,inhibit,MKC-8866,IRE1,MKC8866,Inhibitor,MKC 8866
CAS:
1338934-59-0
MF:
C18H19NO7
MW:
361.35
Mol File:
1338934-59-0.mol
More
Less

MKC8866 Chemical Properties

Boiling point:
620.0±55.0 °C(Predicted)
Density 
1.373±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO:16.67(Max Conc. mg/mL);46.13(Max Conc. mM)
form 
A solid
pka
6.20±0.20(Predicted)
color 
Light yellow to yellow
More
Less

MKC8866 Usage And Synthesis

Biological Activity

MKC8866 (IRE1-IN-8866) is a salicylaldehyde analog, a specific IRE1α RNase inhibitor with IC50 of 0.29 μM against human IRE1α in vitro.

target

TargetValue
hIRE1α
(Cell-free assay)
0.29 μM

MKC8866Supplier

ChemShuttle, Inc.
Tel
0510-83588313-802 18800520310;
Email
sales@chemshuttle.com
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Email
info@efebio.com
Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Email
klq@cw-bio.com
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Email
2853530910@QQ.com