PRIMIN Chemical Properties

Melting point:

77-79℃

Boiling point:

163 °C(Press: 3 Torr)

Density 

1.06±0.1 g/cm3 (20 ºC 760 Torr)

solubility 

Acetonitrile: soluble; Ethanol: soluble; Ethyl Acetate: soluble; Methanol: soluble

form 

A solid

PRIMIN Usage And Synthesis

Description

Primin is the allergen of Primula obconica. Occupational contact dermatitis occurs mainly in florists and horticulturists.

Uses

Primin can be prepared to use for SAR docking and antioxidant activity due to the activity of COX/5-LOX inhibitors with quinone and resorcinol core. It can also be used for its cytotoxic mechanisms toward human acute lymphoblastic leukemia, multiple myeloma and acute myeloid leukemia cells.

Definition

ChEBI: A member of the class of 1,4-benzoquinones having a methoxy substituent at the 2-position and a pentyl substituent at the 6-position.

Contact allergens

Primin is the major allergen of Primula obconica Hance (Primulaceae family). Allergic contact dermatitis is mainly occupational, occurring in florists and horticulturists.

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