4-(4-Pyridyl)Benzoic Acid
4-(4-Pyridyl)Benzoic Acid Basic information
- Product Name:
- 4-(4-Pyridyl)Benzoic Acid
- Synonyms:
-
- 5-TAMRA-PEG4-Methyltetrazine
- CAS:
- 2163772-19-6
- MF:
- C42H45N7O8
- MW:
- 775.86
- Mol File:
- 2163772-19-6.mol
4-(4-Pyridyl)Benzoic Acid Usage And Synthesis
Description
TAMRA-PEG4-Methyltetrazine is a fluorescent dye compound which can be labled to other macromolecule via click chemistry with TCO. Rhodamine is a commonly used red fluorescent dye tracer in biology for staining cells, tissues, biomarkers or nanoparticles. It has peak fluorescence emission at 572-575 nm.
Uses
TAMRA-PEG4-methyltetrazine is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-methyltetrazine contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
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