4-(TRIFLUOROMETHYL)PHENETHYL ALCOHOL Chemical Properties

Boiling point:

218.2±35.0 °C(Predicted)

Density 

1.253 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.463(lit.)

Flash point:

52 °C

storage temp. 

2-8°C

pka

14.69±0.10(Predicted)

Appearance

Colorless to pink Liquid

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-36

Safety Statements 

26-36

WGK Germany 

2

HS Code 

2906290090

4-(TRIFLUOROMETHYL)PHENETHYL ALCOHOL Usage And Synthesis

Uses

4-(Trifluoromethyl)-benzeneethanol is an intermediate used to prepare substituted phenylpropanoic acid derivatives as selective human PPARα activators.It is also used to synthesize PI3Kγ-kinase inhibitors.

References

[1] Patent: WO2005/49613, 2005, A1. Location in patent: Page/Page column 48-49
[2] European Journal of Organic Chemistry, 2016, vol. 2016, # 35, p. 5803 - 5806
[3] Patent: WO2006/120481, 2006, A2. Location in patent: Page/Page column 19
[4] Patent: US2009/227640, 2009, A1. Location in patent: Page/Page column 49
[5] Patent: US2009/291993, 2009, A1. Location in patent: Page/Page column 12; 21

4-(TRIFLUOROMETHYL)PHENETHYL ALCOHOL(2968-93-6)Related Product Information

• 4-(Trifluoromethyl)-DL-phenylglycine
• 2-CHLORO-4-FLUOROPHENYLACETIC ACID
• 2,6-DICHLORO-4-(TRIFLUOROMETHYL)PHENYLACETIC ACID
• 4-(TRIFLUOROMETHYL)MANDELIC ACID
• 2-NITRO-4-(TRIFLUOROMETHYL)PHENYLACETIC ACID
• 4-(Trifluoromethyl)phenylacetic acid
• 2,4-BIS(TRIFLUOROMETHYL)PHENYLACETIC ACID
• 3-FLUORO-4-(TRIFLUOROMETHYL)PHENYLACETIC ACID
• (4-Perfluorotolyl)acetic acid
• ETHYL ALPHA-CYANO-2-NITRO-4-(TRIFLUOROMETHYL)PHENYLACETATE
• ETHYL OXO-(4-TRIFLUOROMETHYLPHENYL)ACETATE
• ETHYL 2-[2,4-BIS(TRIFLUOROMETHYL)PHENYL]-2-OXOACETATE
• METHYL 2-CYANO-2-[2-NITRO-4-(TRIFLUOROMETHYL)PHENYL]ACETATE
• 2-(2-THIENYL)-2-[4-(TRIFLUOROMETHYL)PHENYL]ACETIC ACID
• ETHYL 2-FLUORO-4-(TRIFLUOROMETHYL)PHENYLACETATE
• 2,3-Difluoro-4-(trifluoromethyl)phenylacetic acid
• 4-[CARBOXY-(4-TRIFLUOROMETHYL-PHENYL)-METHYL]-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER HYDROCHLORIDE
• 4-(TRIFLUOROMETHYL)PHENYLGLYCINE