Dipivefrin hydrochloride CAS#: 64019-93-8

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Dipivefrin hydrochloride

Basic information Safety Supplier Related

Dipivefrin hydrochloride Basic information

Product Name:

Dipivefrin hydrochloride

Synonyms:

dipivalylepinephrinehydrochloride
dipivefrinehydrochloride
dipivefrinhydrochloride
hydrochloride,(+-)-este
propanoicacid,2,2-dimethyl-,4-(1-hydroxy-2-(methylamino)ethyl)-1,2-phenylene
Progate
Propanoic acid,2,2-diMethyl-, 1,1'-[4-[1-hydroxy-2-(MethylaMino)ethyl]-1,2-phenylene] ester,hydrochloride (1:1)
DIPIVEFRIN HYDROCHLORIDE (200 MG)

CAS:

64019-93-8

MF:

C19H30ClNO5

MW:

387.8982

EINECS:

264-609-5

Product Categories:

Mol File:

64019-93-8.mol

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Dipivefrin hydrochloride Chemical Properties

Melting point:: 158-159°
storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility: Freely soluble in water, very soluble in methanol, freely soluble in ethanol (96 per cent) and in methylene chloride.
pka: 8.40(at 25℃)
form: Solid
color: White to Off-White
InChI: InChI=1S/C19H29NO5.ClH/c1-18(2,3)16(22)24-14-9-8-12(13(21)11-20-7)10-15(14)25-17(23)19(4,5)6;/h8-10,13,20-21H,11H2,1-7H3;1H
InChIKey: VKFAUCPBMAGVRG-UHFFFAOYSA-N
SMILES: C1(OC(=O)C(C)(C)C)=CC(=CC=C1OC(=O)C(C)(C)C)C(O)CNC.Cl

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Safety Information

RIDADR: UN 2811 6.1 / PGIII
HS Code: 2922504500

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Dipivefrin hydrochloride Usage And Synthesis

Description

Dipivefrin hydrochloride is an antiglaucoma prothrombotic drug that is hydrolyzed to its active compound epinephrine by esterases in the cornea.

Chemical Properties

White or almost white, crystalline powder.

Uses

Dipivefrine Hydrochloride acts as an anti-glaucoma agent.

Uses

Adrenergic (ophthalmic)

Definition

ChEBI: The hydrochloride salt of dipivefrin. It is used topically as eye drops to reduce intra-ocular pressure in the treatment of open-angle glaucoma or ocular hypertension.

brand name

Akpro (Akorn); Propine (Allergan).

in vivo

Dipivefrin hydrochloride (0.3-10 μg/kg; i.p.;) induces enhancement of memory involves central beta- but not alpha-adrenergic mechanisms.

Dipivefrin hydrochlorideSupplier

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