ChemicalBook > Product Catalog > Pharmaceutical intermediates > Bulk Drug Intermediates > 7 8-DIHYDROXY-4-PHENYLCOUMARIN
7 8-DIHYDROXY-4-PHENYLCOUMARIN
7 8-DIHYDROXY-4-PHENYLCOUMARIN Basic information
- Product Name:
- 7 8-DIHYDROXY-4-PHENYLCOUMARIN
- Synonyms:
-
- 7,8-dihydroxy-4-phenyl-2-chromenone
- 7,8-dihydroxy-4-phenyl-chromen-2-one
- 7,8-dihydroxy-4-phenylchromen-2-one
- LDN 0063260
- Coumarin 8
- 4-Phenyldaphnetin
- 2H-1-Benzopyran-2-one, 7,8-dihydroxy-4-phenyl-
- 4-Phenyl-7,8-dihydroxycoumarin
- CAS:
- 842-01-3
- MF:
- C15H10O4
- MW:
- 254.24
- Product Categories:
-
- API intermediates
- Building Blocks
- Coumarins
- Heterocyclic Building Blocks
- Mol File:
- 842-01-3.mol
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7 8-DIHYDROXY-4-PHENYLCOUMARIN Chemical Properties
- Melting point:
- 190-195 °C (lit.)
- storage temp.
- Store at -20°C
- solubility
- DMSO : 100 mg/mL (393.33 mM; Need ultrasonic)
- form
- Solid
- color
- Off-white to yellow
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7 8-DIHYDROXY-4-PHENYLCOUMARIN Usage And Synthesis
Uses
4-Phenyl-7,8-dihydroxycoumarin is a coumarin derivative and can be used for bronchiectasiss research[1].
References
[1] Liang SC, et al. Inhibition of human catechol-O-methyltransferase-mediated dopamine O-methylation by daphnetin and its Phase II metabolites. Xenobiotica. 2017 Jun;47(6):498-504. DOI:10.1080/00498254.2016.1204567
[2] A kind of Chinese medicine and western medicine combination for treating bronchiectasiss and preparation method thereof. Patent CN106491853
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