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L-Leu-Leu-Leu

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L-Leu-Leu-Leu Basic information

Product Name:
L-Leu-Leu-Leu
Synonyms:
  • (2S)-2-[[(2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoic acid
  • (2S)-2-[[(2S)-2-[[(2S)-2-amino-4-methyl-pentanoyl]amino]-4-methyl-pentanoyl]amino]-4-methyl-valeric acid
  • (2S)-2-[[(2S)-2-[[(2S)-2-azanyl-4-methyl-pentanoyl]amino]-4-methyl-pentanoyl]amino]-4-methyl-pentanoic acid
  • (S)-2-((S)-2-((S)-2-Amino-4-methylpentanamido)-4-methylpentanamido)-4-methylpentanoic acid
  • Leu-Leu-Leu-OH≥ 96% (Elemental Analysis)
  • H-LEU-LEU-LEU-OH
  • LEU-LEU-LEU
  • L-LEUCYL-L-LEUCYL-L-LEUCINE
CAS:
10329-75-6
MF:
C18H35N3O4
MW:
357.49
Product Categories:
  • Peptides
  • Tripeptides
  • Dipeptides and Tripeptides
Mol File:
10329-75-6.mol
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L-Leu-Leu-Leu Chemical Properties

Boiling point:
589.6±45.0 °C(Predicted)
Density 
1.057
storage temp. 
−20°C
pka
3.39±0.10(Predicted)
InChI
InChI=1S/C18H35N3O4/c1-10(2)7-13(19)16(22)20-14(8-11(3)4)17(23)21-15(18(24)25)9-12(5)6/h10-15H,7-9,19H2,1-6H3,(H,20,22)(H,21,23)(H,24,25)/t13-,14-,15-/m0/s1
InChIKey
DNDWZFHLZVYOGF-KKUMJFAQSA-N
SMILES
C(O)(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)N
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Safety Information

WGK Germany 
3

MSDS

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L-Leu-Leu-Leu Usage And Synthesis

Description

The tripeptide trileucine (Leu-Leu-Leu) is found in casein and soy protein. This substance could increase the endothelial release of TXB2 which is a stable marker of TXA2. Inhibitor of human liver alanine aminopeptidase, Ki 0.054 mM. The addition of trileucine improved the aerosol performance and stability of spray-dried powders for inhalation.

Chemical Properties

LEU-LEU-LEU is also known Trileucine. It is a white solid powder and soluble in DMSO.

Uses

Leu-Leu-Leu could be used to synthesize Cl-.H2+-Leu-Leu-Leu-OMe (a hydrochloric acid salt of Peptide derivative IIa).

Definition

ChEBI: A tripeptide formed from three L-leucine residues.

storage

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

L-Leu-Leu-LeuSupplier

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