1-METHYL-3-INDOLEACETIC ACID Chemical Properties

Melting point:

126-128 °C (lit.)

Boiling point:

392.0±17.0 °C(Predicted)

Density 

1.20±0.1 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

Chloroform, Methanol

form 

Crystalline Powder

pka

4.53±0.30(Predicted)

color 

White to tan

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-37/38-41

Safety Statements 

26-39

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

2933998090

1-METHYL-3-INDOLEACETIC ACID Usage And Synthesis

Chemical Properties

Light Brown Solid

Uses

• Reactant for enantioselective preparation of α-aryl alkylcarboxylic acids
• Reactant for preparation of PKC inhibitor methylindolylpyridinylmethylpiperidinylindolylpyrroledione for protein kinase C imaging
• Reactant for stereoselective preparation of δ-lactones via Michael addition/lactonization with unsaturated carboxylates
• Reactant for stereoselective preparation of vindorosine, vindoline, and analogs
• Reactant for preparation of (indolyl)pyrrol-2-ones as VEGF-R inhibitors, antiangiogenic agents, and protein kinase inhibitors
• Reactant for synthesis of 3-aryl-5-alkyl-2,5-dihydrofuran-2-ones and their carbanalogues as antifungal agents

Uses

1-Methylindole-3-acetic Acid is a N-methylated derivative of Indole-3-acetic acid, a natural auxin, with plant growth regulating activity.

General Description

1-Methyl-3-indoleacetic acid is an indole derivative. Direct and riboflavin- or Rose-Bengal-sensitized photo-oxidation of 1-methyl-3-indoleacetic acid in aqueous buffer (pH 5 or pH 8) containing 10% methanol has been studied.

1-METHYL-3-INDOLEACETIC ACID(1912-48-7)Related Product Information

• PROGLUMETACIN MALEATE
• Acemetacin
• 1-(4-CHLOROBENZOYL)-5-METHOXY-2-METHYL-3-INDOLEACETIC ACID
• zidometacin
• 1-METHYL-3-INDOLEACETIC ACID
• 2-METHYL-3-INDOLEACETIC ACID
• 5-METHOXY-2-METHYL-3-INDOLEACETIC ACID,5-METHOXY-2-METHYL-3-INDOLEACETIC ACID 98%
• Indole-3-acetic acid
• 2-(1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-1H-INDOL-3-YL)ACETIC ACID
• PEAK E
• 2-[1-(6-CHLORO-3-PYRIDAZINYL)-1H-INDOL-3-YL]ACETIC ACID
• 4-(4-(TERT-BUTYL)PHENYL)-2-(1-METHYLINDOL-3-YL)-4-OXOBUTANOIC ACID
• 2-[1-(4-FLUOROBENZYL)-1H-INDOL-3-YL]ACETIC ACID
• 4-(4-BROMOPHENYL)-2-(1-METHYLINDOL-3-YL)-4-OXOBUTANOIC ACID
• 2-[1-(3-CHLOROBENZYL)-1H-INDOL-3-YL]ACETIC ACID
• METHYL 2-(1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-1H-INDOL-3-YL)-3-([(4-NITROBENZYL)OXY]IMINO)PROPANOATE
• TERT-BUTYL 3-[ETHOXY(OXO)ACETYL]-1H-INDOLE-1-CARBOXYLATE
• METHYL 2-(1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-1H-INDOL-3-YL)-3-(DIMETHYLAMINO)ACRYLATE