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2-Chloromandelic acid

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2-Chloromandelic acid Basic information

Product Name:
2-Chloromandelic acid
Synonyms:
  • TIMTEC-BB SBB003705
  • o-chloromandelic acid
  • 2-Chloro-alpha-hydroxyphenylaceticacid
  • Methyl-(2-chlorophenyl) hydroxy carboxylic acid
  • Chloromandelic Acid DL-
  • Benzeneacetic acid, 2-chloro-α-hydroxy-
  • DL-2-CHLOROMANDELIC ACID
  • 2-(2-CHLOROPHENYL)-2-HYDROXYACETIC ACID
CAS:
10421-85-9
MF:
C8H7ClO3
MW:
186.59
EINECS:
233-900-9
Product Categories:
  • C8
  • Carbonyl Compounds
  • Miscellaneous
  • Organic acids
  • Carboxylic Acids
Mol File:
10421-85-9.mol
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2-Chloromandelic acid Chemical Properties

Melting point:
90-93 °C(lit.)
Boiling point:
266.91°C (rough estimate)
Density 
1.3245 (rough estimate)
refractive index 
1.5250 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly, Sonicated), Methanol (Slightly)
form 
Crystalline Powder
pka
3.30±0.10(Predicted)
color 
White to pale cream
Water Solubility 
Very soluble in water.
BRN 
2367070
Stability:
Hygroscopic
CAS DataBase Reference
10421-85-9(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
24/25-36-26
WGK Germany 
3
HS Code 
29181990

MSDS

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2-Chloromandelic acid Usage And Synthesis

Chemical Properties

White to pale cream crystalline powder

Uses

2-Chloromandelic acid, is used as a pharmaceutical intermediate as well as in the medicine industry. It is used as a intermediate of clopidrogrel.

General Description

2-Chloromandelic acid (2-ClMA) is a mandelic acid derivative. A report based on its solid state-NMR, X-ray powder diffraction (XPRD) and Fourier transform infrared spectroscopy (FTIR) data reveals that in solid state 2-ClMA exists as a racemic compound. The study also suggests that the crystals of racemic 2-ClMA belongs the monoclinic space group P21/c. The efficiency of (R)-(+)-N-benzyl-1-phenylethylamine in resolving racemate 2-ClMA has been investigated.

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