Basic information Safety Supplier Related

COENZYME Q4

Basic information Safety Supplier Related

COENZYME Q4 Basic information

Product Name:
COENZYME Q4
Synonyms:
  • COENZYME Q4
  • 2,3-DIMETHOXY-5-METHYL-6-(GERANYLGERANYL)-1,4-BENZOQUINONE
  • Q-4
  • UBIQUINONE-20
  • UBIQUINONE-4
  • 2,3-dimethoxy-5-methyl-6-[(2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraenyl]cyclohexa-2,5-diene-1,4-dione
  • Ubiquinone Q4
  • 2,3-Dimethoxy-5-methyl-6-(geranylgeranyl)-1,4-benzoquinone, Q-4, Ubiquinone-20, Ubiquinone-4
CAS:
4370-62-1
MF:
C29H42O4
MW:
454.64
EINECS:
215-668-0
Mol File:
4370-62-1.mol
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COENZYME Q4 Chemical Properties

Boiling point:
584.1±50.0 °C(Predicted)
Density 
1.01±0.1 g/cm3(Predicted)
storage temp. 
-20°C
BRN 
2066531
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
3
8-10

MSDS

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COENZYME Q4 Usage And Synthesis

Uses

Coenzyme Q4 (CoQ4) is a 4 isoprenyl group member of a family of ubiquinones that share a quinine chemical group but differ in the number of isoprenyl chemical subunits in their tail. The CoQ compounds are lipid soluble components of cell membranes where they perform multiple functions such as electron and proton transport. The most well studied CoQ compound is CoQ10. CoQ4 is frequently used in comparison studies on the effect of isoprenyl chain length on CoQ functions or distribution.

Definition

ChEBI: Coenzyme Q4 is a member of ubiquinones.

Biochem/physiol Actions

Increases the fluorescence polarization of perylene incorporated into ubiquinone-depleted mitochondrial and bilayer vesicles prepared from mitochondrial phospholipids

Purification Methods

It is a redoil which can be purified by chromatography on SiO2 plates and eluted with Et2O/hexane. The purity is checked by HPLC (silica column using 7% Et2O/hexane). It has max 270 nm ( 14,800) in pet ether. [NMR and MS: Naruta J Org Chem 45 4097 1980, cf Morton Biochemical Spectroscopy (Adam Hilger, London, 1975) p 491]. It has also been dissolved in MeOH/EtOH (1:1 v/v) and kept at 5o until crystals appear [Lester & Crane Biochim Biophys Acta 32 497 1958].

COENZYME Q4Supplier

Syntechem Co.,Ltd
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Shanghai T&W Pharmaceutical Co., Ltd.
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Sigma-Aldrich
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Hubei Yangxin Medical Technology Co., Ltd.
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Aikon International Limited
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18626450290
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yftan@aikonchem.com