Oxyphenonium bromide
Oxyphenonium bromide Basic information
- Product Name:
- Oxyphenonium bromide
- Synonyms:
-
- ba-5473
- c5473
- diethyl(2-hydroxyethyl)methylammoniumbromidealpha-phenylcyclohexaneglycolat
- oxifenon
- oxyfenon
- oxyphenon
- 2-[(Cyclohexylhydroxyphenylacetyl)oxy]-N,N,-diethyl-N-methylethylammonium bromide
- Oxyphenonium
- CAS:
- 50-10-2
- MF:
- C21H34BrNO3
- MW:
- 428.4
- EINECS:
- 200-010-7
- Product Categories:
-
- ANTRENYL
- Mol File:
- 50-10-2.mol
Oxyphenonium bromide Chemical Properties
- Melting point:
- 189-194° from ethyl acetate + alc
- Density
- 1.2584 (rough estimate)
- refractive index
- 1.6200 (estimate)
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- A solid
- color
- White to Off-White
MSDS
- Language:English Provider:SigmaAldrich
Oxyphenonium bromide Usage And Synthesis
Originator
A-Spasm ,Acme Laboratories Ltd.
Uses
anticholinergic, anticonvulsant
Manufacturing Process
1 mol cycloxehylhydroxyphenylacetic acid methyl ester was mixed with 1 mol 2-diethylaminoethanol in presence of 1 mol sodium methylate to give cycloxehylhydroxyphenylacetic acid 2-diethylamino-ethyl ester.
5 parts by weight of it was dissolved in 50 volumes glacial acetic acid and a gaseous methyl bromide was introduced. The mixture was heated to about 50°C and crystallization of cycloxehylhydroxyphenylacetic acid diethylaminoethyl ester methyl bromide has shortly after begun. On cooling the crystals was filtered off and recrystallized from mixture of ethyl acetate ant a little ethanol to give the oxyphenonium bromide. MP: 189°-191°C.
brand name
Antrenyl (Novartis).
Therapeutic Function
Anticholinergic, Spasmolytic
Safety Profile
Poison by ingestion, intramuscular, intraperitoneal, intravenous, and subcutaneous routes. Human systemic effects by ingestion: change in heart rate. When heated to decomposition it emits very toxic fumes of NOx, NH3, and Brí.
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Oxyphenonium bromide(50-10-2)Related Product Information
- Ipratropium bromide monohydrate
- Allyl bromide
- CHLOROPHOSPHONAZO III
- Pinaverium bromide
- Tetrapropylammonium bromide
- Ethidium bromide
- Glycopyrrolate
- Ammonium bromide
- Rocuronium bromide
- Benzyldodecyldimethylammonium bromide
- Sodium bromate
- Tetraethylammonium bromide
- Tiotropium bromide
- prifinium bromide
- Tetrabutylammonium bromide
- Methyl bromide
- ACETYLCHOLINE BROMIDE
- 2-(2-HYDROXYPHENYL)PROPIONIC ACID