3-ETHOXYSALICYLALDEHYDE Chemical Properties

Melting point:

66-68 °C (lit.)

Boiling point:

263-264 °C (lit.)

Density 

1.1097 (rough estimate)

refractive index 

1.4500 (estimate)

Flash point:

263-264°C

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

form 

powder to crystal

pka

8.30±0.10(Predicted)

color 

Light yellow to Brown to Dark green

Water Solubility 

Soluble in cold water. Insoluble in methanol, ethanol, acetone and acetonitrile

Sensitive 

Air Sensitive

CAS DataBase Reference

492-88-6(CAS DataBase Reference)

EPA Substance Registry System

Benzaldehyde, 3-ethoxy-2-hydroxy- (492-88-6)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

RTECS 

CU6123000

TSCA 

Yes

HS Code 

29124990

Toxicity

LD50 ipr-mus: 360 mg/kg COREAF 238,2576,54

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

3-ETHOXYSALICYLALDEHYDE Usage And Synthesis

Uses

3-Ethoxysalicylaldehyde was used in the preparation of:

• Schiff base ligand via condensation with trans-1,2-diaminocyclohexane
• substituted salen-type Schiff base ligands
• a new Schiff base, 2-ethoxy-6-[(3-methylaminopropylimino)methyl]phenol, via reaction with N-methylpropane-1,3-diamine

Safety Profile

A poison by intraperitoneal andintravenous routes. When heated to decomposition itemits acrid smoke and irritating vapors.

3-ETHOXYSALICYLALDEHYDE(492-88-6)Related Product Information

• PSOROMIC ACID
• 3-ETHOXYSALICYLALDEHYDE
• cinepaxadil
• Iprocrolol
• 2,3-Dihydro-1,4-benzodioxine-5-carboxylic acid
• GOSSYPIN
• APIGENIN 6-GLUCOSYL-7-O-METHYL ETHER
• 2,3-DIHYDRO-1,4-BENZODIOXINE-5-CARBALDEHYDE
• Puerarin
• dipyrocetyl
• Salicylaldehyde
• 3-Ethoxybenzaldehyde
• Purpuromycin
• 3-ETHOXY-2-HYDROXY-BENZOIC ACID
• cervinomycin A1 triacetate
• 2,3-DIBROMO-5-ETHOXY-6-HYDROXYBENZALDEHYDE
• 5-BROMO-3-ETHOXY-2-HYDROXYBENZALDEHYDE
• 3'-ACETOXY-2',4'-DIMETHOXYACETOPHENONE