3-BROMO-5-NITROBENZOTRIFLUORIDE Chemical Properties

Boiling point:

223.7±35.0 °C(Predicted)

Density 

1.788±0.06 g/cm3(Predicted)

refractive index 

1.515

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Oil

color 

Colourless

CAS DataBase Reference

630125-49-4(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

20/21/22-36/37/38-36/38

Safety Statements 

26-36/37/39-36/37

HazardClass 

IRRITANT

HS Code 

29049090

3-BROMO-5-NITROBENZOTRIFLUORIDE Usage And Synthesis

Description

3-Bromo-5-nitrobenzotrifluoride is an important organic synthetic compound and a pharmaceutical intermediate component. It can be used in the preparation of SOS1 degraders and nilotinib hydrochloride.

Chemical Properties

Yellow liquid

Uses

3-Bromo-5-nitrobenzotrifluoride is an efficient D-glucosamine-based copper catalyst for C-X couplings and its application in synthesis of nilotinib intermediate. 3-Bromo-5-nitrobenzotrifluoride is also an intermediate for Nilotinib (N465300).

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