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5-METHOXY-2-NITROANILINE

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5-METHOXY-2-NITROANILINE Basic information

Product Name:
5-METHOXY-2-NITROANILINE
Synonyms:
  • 3-Amino-4-nitroanisole 2-Amino-4-methoxy-1-nitrobenzene
  • 3-Amino-4-nitroanisole, 6-Nitro-m-anisidine
  • BUTTPARK 148\07-49
  • 3-AMINO-4-NITROANISOLE
  • 5-METHOXY-2-NITROANILINE
  • 5-METHOXY-2-NITROPHENYLAMINE
  • 5-Methoxy-2-nitrobenzenamine
  • 6-Nitro-m-anisidine
CAS:
16133-49-6
MF:
C7H8N2O3
MW:
168.15
EINECS:
240-293-4
Product Categories:
  • Anilines, Aromatic Amines and Nitro Compounds
  • Anilines, Amides & Amines
  • Anisoles, Alkyloxy Compounds & Phenylacetates
  • Nitro Compounds
Mol File:
16133-49-6.mol
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5-METHOXY-2-NITROANILINE Chemical Properties

Melting point:
131°C
Boiling point:
337.07°C (rough estimate)
Density 
1.2089 (estimate)
refractive index 
1.6010 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
-0.61±0.25(Predicted)
color 
Yellow
λmax
366nm(Cyclohexane)(lit.)
InChIKey
QEHVRGACCVLLNN-UHFFFAOYSA-N
CAS DataBase Reference
16133-49-6(CAS DataBase Reference)
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Safety Information

Hazard Codes 
T,Xi
Risk Statements 
20/21/22-36/37/38-43
Safety Statements 
26-36/37/39-36/37
WGK Germany 
3
HS Code 
2922290090
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5-METHOXY-2-NITROANILINE Usage And Synthesis

Uses

5-Methoxy-2-nitrobenzenamine is used in the synthesis of methoxybenzimidazole compounds as inhibitors of PI3K, used in the therapeutic treatment of cancer. Also used in the synthesis of NR2B-selective NMDA receptor antagonists in the treatment of a range of nervous system disorders

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