4-Methoxyphenylacetone Chemical Properties

Melting point:

<-15 °C

Boiling point:

145 °C/25 mmHg (lit.)

Density 

1.067 g/mL at 25 °C (lit.)

vapor pressure 

1.37Pa at 25℃

FEMA 

2674 | 1-(P-METHOXYPHENYL)-2-PROPANONE

refractive index 

n20/D 1.525(lit.)

Flash point:

215 °F

storage temp. 

Sealed in dry,Room Temperature

solubility 

Methyl Acetate: 50 mg/ml

form 

Liquid

color 

Clear light yellow to yellow-green

Odor

at 10.00 % in dipropylene glycol. sweet fruity creamy spicy green anisic balsamic licorice fennel

Odor Type

fruity

Water Solubility 

3.084g/L at 25℃

JECFA Number

813

BRN 

2044332

InChIKey

WFWKNGZODAOLEO-UHFFFAOYSA-N

LogP

1.55 at 25℃

CAS DataBase Reference

122-84-9(CAS DataBase Reference)

NIST Chemistry Reference

2-Propanone, 1-(4-methoxyphenyl)-(122-84-9)

EPA Substance Registry System

2-Propanone, 1-(4-methoxyphenyl)- (122-84-9)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

23-24/25

WGK Germany 

2

RTECS 

UC2990000

Hazard Note 

Irritant

TSCA 

Yes

HS Code 

29145000

Toxicity

LD50 orl-rat: 3330 mg/kg FCTXAV 17,857,79

MSDS

• Language:English Provider:4-Methoxyphenylacetone
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

4-Methoxyphenylacetone Usage And Synthesis

Aroma

Mild, yet somewhat "gassy" Hawthorne-Anise type odor of good tenacity. It has some resemblance to Methylacetophenone, but is not nearly as harsh or pungent.

Description

l-(p-Methoxyphenyl)-2-propanone has an odor and taste similar to anise. May be obtained by boiling α- or β-anetholglycol with a 20% solution of sulfuric acid, or from l-(p-methoxyphenyl)- propan-l,2-ol by treatment with diluted sulfuric acid.

Chemical Properties

1-(p-Methoxyphenyl)-2-propanone has an odor and taste similar to anise.

Chemical Properties

Pale Yellow Liquid

Occurrence

Reported found in Chinese star anise and in Russian star anise; also reported found in sweet and common fen nel, chervil (Anthriscus cerefolium) and Illicium verum and cherry

Uses

A volatile compound released by flowering plants to attractant insects

Application

4-Methoxyphenylacetone is used occasionally in perfumes, but more frequent ly in flavor compositions. In fruit and imitation Vanilla, sometimes in Walnut or Cherry flavors, it may be used in traces, equivalent to 0.5 to 5 ppm in the finished product.

Definition

ChEBI: 1-(4-Methoxyphenyl)-2-propanone is an alkylbenzene.

Preparation

Obtained by boiling α- or β-anetholglycol with a 2% solution of sulfuric acid, or from 1-(p-methoxyphenyl)-propan-1,2-ol by treatment with diluted sulfuric acid.

Taste threshold values

Taste characteristics at 15 ppm: sweet spicy, with green anisic, minty nuances.

Synthesis Reference(s)

The Journal of Organic Chemistry, 61, p. 1748, 1996 DOI: 10.1021/jo9518314

General Description

Asymmetric amination of 4-methoxyphenylacetone was studied.

Flammability and Explosibility

Not classified

Safety Profile

Moderately toxic by ingestion andother routes. A skin irritant. A flammable liquid.

4-Methoxyphenylacetone(122-84-9)Related Product Information

• Citric acid monohydrate
• Tribenuron methyl
• Thiophanate-methyl
• Methoxypropiophenone
• R-(-)-5-(2-Amino-propyl)-2-methoxy-benzenesulfonamide
• Tamsulosin hydrochloride
• 4-Formylbenzoic acid
• 4-Methoxybenzyl cyanide
• Methyl acetate
• Methyl salicylate
• 4-Methoxyphenylhydrazine hydrochloride
• Kresoxim-methyl
• 4-METHOXYPHENETHYL ALCOHOL
• Methoxyacetone
• METSULFURON METHYL
• 4-Methoxybenzenesulfonyl chloride
• Methyl
• Rotenone