2-Acetoxy-2-methylpropionyl bromide Chemical Properties

Boiling point:

75-77 °C12 mm Hg(lit.)

Density 

1.431 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.457

Flash point:

>230 °F

storage temp. 

2-8°C

solubility 

soluble in Chloroform, Methanol

form 

liquid

color 

Clear, pale yellow

Sensitive 

Moisture Sensitive

BRN 

2432585

CAS DataBase Reference

40635-67-4(CAS DataBase Reference)

Safety Information

Hazard Codes 

C

Risk Statements 

14-34-37

Safety Statements 

26-36/37/39-45

RIDADR 

UN 3265 8/PG 2

WGK Germany 

3

F 

10-19

HazardClass 

8

PackingGroup 

II

HS Code 

29181980

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2-Acetoxy-2-methylpropionyl bromide Usage And Synthesis

Chemical Properties

light yellow clear liquid

Uses

1-Bromocarbonyl-1-methylethyl acetate (α-Acetoxyisobutyryl bromide) may be used:

• in the chemoenzymatic synthesis of (1R,2S)-1,2-epoxy-1,2-dihydroacridine (acridine 1,2-oxide)
• in the synthesis of protected 3′-deoxyadenosine and 3′-deoxyguanosine
• as reagent for deoxygenation of vicinal diols, as well as in the preparation of 2′,3′-dideoxycytidine and other dideoxy and deoxynucleosides from the corresponding ribo series.

General Description

1-Bromocarbonyl-1-methylethyl acetate (α-Acetoxyisobutyryl bromide) participates in the conversion of adenosine to trans-3′(2′)-bromo-2′(3′)-acetates, via glycosyl cleavage.

2-Acetoxy-2-methylpropionyl bromide(40635-67-4)Related Product Information

• Rocuronium bromide
• POLY(VINYL ACETATE)
• Methyl acetate
• Allyl bromide
• Sodium bromate
• Benzyl bromide
• Glatiramer acetate
• Sodium triacetoxyborohydride
• Bromoacetyl bromide
• Ethidium bromide
• Ethyl acetate
• Acetoxyacetic acid
• Sodium acetate
• Vinyl acetate
• SILICON TETRAACETATE
• Tocopheryl acetate
• Butyl acetate
• Propionyl bromide