D-MANNOHEPTULOSE
D-MANNOHEPTULOSE Basic information
- Product Name:
- D-MANNOHEPTULOSE
- Synonyms:
-
- d-Manno-[UL-13C7]hept-2-ulose
- D-Mannoketoheptose
- Ai3-61577
- D-Manno-heptulose (8ci)
- Einecs 222-795-5
- Nsc 226836
- ALPHA-D-MANNOHEPTULOSE
- MANNOHEPTULOSE
- CAS:
- 3615-44-9
- MF:
- C7H14O7
- MW:
- 210.18
- EINECS:
- 222-795-5
- Product Categories:
-
- carbohydrate
- Carbohydrates
- Carbohydrates & Derivatives
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Mol File:
- 3615-44-9.mol
D-MANNOHEPTULOSE Chemical Properties
- Melting point:
- 148-150°C
- alpha
- D20 +29° (c = 2 in H2O)
- Boiling point:
- 628.0±55.0 °C(Predicted)
- Density
- 1.645±0.06 g/cm3(Predicted)
- storage temp.
- Refrigerator
- solubility
- Methanol (Slightly), Water (Slightly)
- form
- Solid
- pka
- 11.86±0.20(Predicted)
- color
- White to Off-White
- optical activity
- +29
- Merck
- 13,4686
- BRN
- 1726433
- EPA Substance Registry System
- D-manno-2-Heptulose (3615-44-9)
Safety Information
- Safety Statements
- 24/25
- WGK Germany
- 2
- HS Code
- 29400090
D-MANNOHEPTULOSE Usage And Synthesis
Description
D-Glucose is phosphorylated by glucokinase and three tissue-specific hexokinases to produce glucose-6-phosphate in humans. D-Mannoheptulose is a heptose that inhibits glucokinases and hexokinases from diverse organisms through competition with D-glucose (Ki = 0.25 mM). It blocks glucose oxidation and glucose-mediated insulin release from pancreatic islet cells. D-Mannoheptulose prevents the conversion of glucose to glucose-6-phosphate that can mediate the activation of the carbohydrate response element binding protein. By blocking glucose phosphorylation, D-mannoheptulose causes transient hyperglycemia in dogs when given at 1 g/kg but not at 8 mg/kg, although postprandial energy expenditure is increased at the lower dose.
Chemical Properties
White Solid
Uses
Mannoheptulose occurs naturally in avocado fruit. It is used for normalizing insulin levels and reducing weight.
Definition
ChEBI: D-keto-manno-heptulose is the open chain form of D-manno-heptulose.
D-MANNOHEPTULOSESupplier
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
- Tel
- 021-50135380
- shchemsky@sina.com
- Tel
- 0731-85526065 13308475853
- ivy@hnhbsj.com
- Tel
- +86 (25) 82263158
- Tel
- 010-56205725
- waley188@sohu.com
D-MANNOHEPTULOSE(3615-44-9)Related Product Information
- 3-Heptanone
- D-MANNOHEPTOSE
- Mannatide
- manninotriose
- Mannitol
- D-Mannose
- L(+)-Rhamnose monohydrate
- D-Mannitol
- D-LYXOSE
- D-MANNOHEPTULOSE
- 1,2,3-HEPTANETRIOL
- 2,2'-Oxydipropanol
- (3R,5R)-(-)-3,5-HEPTANEDIOL
- D-MANNO-[1-13C]HEPT-2-ULOSE
- 1-5-ANHYDRO-D-MANNITOL CRYSTALLINE
- 3-Deoxy-D-arabinose
- mannoheptulose hexaacetate
- Rhamnose