Trandolaprilat Chemical Properties

Melting point:

132-134°C

Boiling point:

640.5±55.0 °C(Predicted)

Density 

1.247±0.06 g/cm3(Predicted)

storage temp. 

-20°C Freezer

solubility 

DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)

form 

Solid

pka

2.20±0.10(Predicted)

color 

White to Off-White

Safety Information

HS Code 

29339900

Trandolaprilat Usage And Synthesis

Chemical Properties

Pale Yellow Solid

Uses

A metabolite of Trandolapril, an antihypertensive.

Uses

A labeled metabolite of Trandolapril, an antihypertensive.

Uses

Trandolaprilat (Trandolapril EP Impurity E) is a metabolite of Trandolapril (T713500), an antihypertensive. Angiotensin converting enzyme (ACE) inhibitor.

Definition

ChEBI: Trandolaprilat is a heterobicyclic compound that is trandolapril in which the ethyl ester group has been hydrolysed to the corresponding acid group. It is the active metabolite of the prodrug trandolapril. It has a role as an antihypertensive agent, an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor, a drug metabolite and a human xenobiotic metabolite. It is an organic heterobicyclic compound, a dipeptide, a secondary amino compound, a tertiary carboxamide and a dicarboxylic acid.

Trandolaprilat(87679-71-8)Related Product Information

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