GALANIN (2-29) (RAT) Chemical Properties

Density 

1.51±0.1 g/cm3(Predicted)

storage temp. 

Desiccate at -20°C

form 

Powder

Water Solubility 

Soluble to 0.60 mg/ml in water

Sequence

Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-His-Ala-Ile-Asp-Asn-His-Arg-Ser-Phe-Ser-Asp-Lys-His-Gly-Leu-Thr-NH2

GALANIN (2-29) (RAT) Usage And Synthesis

Description

Peptide agonist for galanin receptors, showing selectivity for GAL2 (Ki values are 85, 9 and 16 nM at rat GAL1, GAL2 and GAL3 receptors respectively).

Uses

Galanin (2-29) (rat) inhibits rat pancreatic protein and CCK-8-stimulated amylase secretion. Galanin (2-29) (rat) is an GAL2R agonist (Ki: 3.5 nM)[1][2].

References

[1] Rossowski WJ, et al. Galanin: structure-dependent effect on pancreatic amylase secretion and jejunal strip contraction. Eur J Pharmacol. 1993 Aug 24;240(2-3):259-67. DOI:10.1016/0014-2999(93)90907-y
[2] Wang S, et al. Molecular cloning and pharmacological characterization of a new galanin receptor subtype. Mol Pharmacol. 1997 Sep;52(3):337-43. DOI:10.1124/mol.52.3.337

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