ACETYL FLUORIDE Chemical Properties

Melting point:

−84 °C(lit.)

Boiling point:

20-21 °C(lit.)

Density 

1,032 g/cm³

vapor pressure 

15.61 psi ( 20 °C)

EPA Substance Registry System

Acetyl fluoride (557-99-3)

Safety Information

Hazard Codes 

C,F

Risk Statements 

34

Safety Statements 

26-36/37/39-45

RIDADR 

UN 3265 8/PG 1

WGK Germany 

3

RTECS 

AP2800000

Hazard Note 

Flammable/Corrosive

HazardClass 

8

PackingGroup 

II

MSDS

• Language:English Provider:SigmaAldrich

ACETYL FLUORIDE Usage And Synthesis

Definition

ChEBI: Acetyl fluoride is an acyl fluoride that is fluoroethane carrying an oxo group at position 1. It is an acyl fluoride and an organofluorine compound.

Preparation

Acetyl fluoride (but not other acyl fluorides) is most conveniently prepared by  addition of Acetyl Chloride to a solution of Potassium Fluoride in AcOH; reaction is immediate. Warming  the solution and condensing the gas gives nearly quantitiative yields. Procedures applicable to the  preparation of a variety of acyl fluorides include reaction of the acid chloride or anhydride with  nucleophilic fluorides and fluorination of the carboxylic acid.

Safety Profile

Poison by inhalation. See also FLUORIDES. When heated to decomposition it emits toxic fumes of F-.

storage

Samples of acetyl fluoride sealed in glass ampoules slowly form a  pyrylium salt.4 Acetyl fluoride is a corrosive lachrymator. Use in a fume hood.

Purification Methods

Purify acetyl fluoride by fractional distillation. It attacks glass and is sold in steel cylinders. [Beilstein 2 H 172, 2 I 79, 2 II 175, 2 III 385, 2 IV 393.] TOXIC and LACHRYMATORY.

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