Basic information Safety Supplier Related

Hydroxy-PEG12-Boc

Basic information Safety Supplier Related

Hydroxy-PEG12-Boc Basic information

Product Name:
Hydroxy-PEG12-Boc
Synonyms:
  • Hydroxy-PEG12-Boc
  • Hydroxy-dPEG12-t-butyl ester
  • PROTAC Linkers,Hydroxy-PEG-12-Boc,HydroxyPEG12Boc,inhibit,Hydroxy PEG12 Boc,Inhibitor
  • 4,7,10,13,16,19,22,25,28,31,34,37-Dodecaoxanonatriacontanoic acid, 39-hydroxy-, 1,1-dimethylethyl ester
  • tert-butyl3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
CAS:
2388521-20-6
MF:
C31H62O15
MW:
674.82
Mol File:
2388521-20-6.mol
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Hydroxy-PEG12-Boc Chemical Properties

Boiling point:
669.5±50.0 °C(Predicted)
Density 
1.092±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
form 
Solid-Liquid Mixture
pka
14.36±0.10(Predicted)
color 
Colorless to off-white
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Hydroxy-PEG12-Boc Usage And Synthesis

Uses

Hydroxy-PEG12-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005

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