Dentonin Chemical Properties

Density 

1.58±0.1 g/cm3(Predicted)

form 

Solid

color 

White to off-white

Sequence

Thr-Asp-Leu-Gln-Glu-Arg-Gly-Asp-Asn-Asp-Ile-Ser-Pro-Phe-Ser-Gly-Asp-Gly-Gln-Pro-Phe-Lys-Asp

Dentonin Usage And Synthesis

Uses

Dentonin (AC-100) is a synthetic fragment derived from MEPE. Dentonin enhances osteogenesis by promoting osteoprogenitor adhesion and facilitates immature adherent cells survival. Dentonin has no significant effect to mature osteoblasts. Dentonin can be used for the research of phosphate homeostasis and bone metabolism[1].

References

[1] Andrew P Sprowson, et al. ASARM-truncated MEPE and AC-100 enhance osteogenesis by promoting osteoprogenitor adhesion. J Orthop Res. 2008 Sep;26(9):1256-62. DOI:10.1002/jor.20606
[2] N Six, et al. Dentonin, a MEPE fragment, initiates pulp-healing response to injury.J Dent Res. 2007 Aug;86(8):780-5. DOI:10.1177/154405910708600818

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