Basic information Safety Supplier Related

Azido-PEG1-Val-Cit-PAB-OH

Basic information Safety Supplier Related

Azido-PEG1-Val-Cit-PAB-OH Basic information

Product Name:
Azido-PEG1-Val-Cit-PAB-OH
Synonyms:
  • Azido-PEG1-Val-Cit-PAB-OH
  • Azide-PEG1-Val-Cit-PABC-OH
CAS:
2055041-40-0
MF:
C23H36N8O6
MW:
520.59
Product Categories:
  • ADC LINKER
Mol File:
2055041-40-0.mol
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Azido-PEG1-Val-Cit-PAB-OH Usage And Synthesis

Description

Azido-PEG1-Val-Cit-PAB-OH is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. Azido group will react with DBCO, BCN or other Alkyne group through click chemistry, PEG spacer increases aqueous solubility.

Azido-PEG1-Val-Cit-PAB-OHSupplier

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
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Xi'an Confluore Biological Technology Co., Ltd.
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