Indole-2-carboxaldehyde Chemical Properties

Melting point:

138-142 °C

Boiling point:

339.1±15.0 °C(Predicted)

Density 

1.278±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

Soluble in Methanol.

pka

15.05±0.30(Predicted)

form 

Solution

color 

Clear pale yellow to grey

Sensitive 

Air Sensitive

InChIKey

SBNOTUDDIXOFSN-UHFFFAOYSA-N

CAS DataBase Reference

19005-93-7(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36

Safety Statements 

26-36

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29339900

Indole-2-carboxaldehyde Usage And Synthesis

Uses

Indole-2-carboxaldehyde is a useful starter in indole and natural product chemistry.

Synthesis Reference(s)

Tetrahedron, 36, p. 2505, 1980 DOI: 10.1016/0040-4020(80)80230-4

Purification Methods

Recrystallise the indole from aqueous MeOH (m 141-142o), Et2O (m 138o) or sublime it in vacuo (m 138o).The N,N-dimethylhydrazone [127280-17-5] has m 105-106o (from hexane/*C6H6). The thiosemicarbazone has m 229o (dec) (from 50% aqueous EtOH) [Doyle et al. J Chem Soc 2854 1956]. The 2,4-dinitrophenylhydrazone has m 315-320o (dec) (from pyridine/MeOH). [Suzuki et al. Chem Pharm Bull Jpn 39 2170 1991, Beilstein 21 III/IV 3754.]

Indole-2-carboxaldehyde(19005-93-7)Related Product Information

• Formaldehyde
• Indoline
• Indometacin
• Indole
• Indole-3-butyric acid
• Indole-3-acetic acid
• Indole-2-carboxylic acid
• Ethyl indole-2-carboxylate
• (1H-INDOL-3-YL)METHANAMINE
• 3-(3-Indolyl)-2-oxopropanoic acid
• INDOLE-3-GLYOXYLYL CHLORIDE
• 1H-Indol-7-amine,2,3-dihydro-(9CI)
• DL-INDOLE-3-LACTIC ACID
• Indole-6-boronic acid
• Indole-3-carboxaldehyde
• Indole-3-carboxylic acid
• Indole-3-carbinol
• Ethyl indole-3-carboxylate