ChemicalBook > Product Catalog > API > Circulatory system drugs > Lipid regulating drugs > simfibrate
simfibrate
simfibrate Basic information
- Product Name:
- simfibrate
- Synonyms:
-
- simfibrate
- 1,3-Propanediol bis[2-(4-chlorophenoxy)-2-methylpropionate]
- Bis[2-(4-chlorophenoxy)-2-methylpropanoic acid] 1,3-propanediyl
- Cholesolvin
- CLY-503
- Sinfibrate
- Propane-1,3-diyl bis(2-(4-chlorophenoxy)-2-methylpropanoate)
- Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-, 1,1'-(1,3-propanediyl) ester
- CAS:
- 14929-11-4
- MF:
- C23H26Cl2O6
- MW:
- 469.35
- EINECS:
- 2389987
- Mol File:
- 14929-11-4.mol
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simfibrate Chemical Properties
- Melting point:
- 51-53°
- Boiling point:
- bp0.03 197-200°; bp0.15 220-230°
- Density
- 1.2623 (estimate)
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simfibrate Usage And Synthesis
Originator
Cholesorbin,Takeda,Japan,1971
Definition
ChEBI: Simfibrate is an organic molecular entity.
Manufacturing Process
A mixture of 22 grams of α-(p-chlorophenoxy)isobutyric acid, 3.8 grams of 1,3-propanediol, 0.5 gram of p-toluenesulfonic acid and 150 ml of xylene was refluxed. When the theoretically calculated amount of water had been removed, the xylene solution was washed with dilute aqueous sodium bicarbonate and then the xylene was distilled off. The residue was distilled under reduced pressure to give 11 grams (47% yield) of 1,3-propanediol bis[α-(p-chlorophenoxy)isobutyrate] boiling at 197° to 200°C/0.03 mm Hg.
Therapeutic Function
Antihyperlipidemic
simfibrateSupplier
LGM Pharma
- Tel
- 1-(800)-881-8210
- inquiries@lgmpharma.com
Aikon International Limited
- Tel
- 025-58851090 13611564524
- lwan@aikonchem.com
Shaanxi Dideu Medichem Co. Ltd
- Tel
- +86-029-89586680 +86-18192503167
- 1026@dideu.com
TargetMol Chemicals Inc.
- Tel
- 4008200310
- marketing@tsbiochem.com
Shaanxi Dideu Newmaterial Co., Ltd.
- Tel
- 029-87576359 15353716720
- 1039@dideu.com
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simfibrate(14929-11-4)Related Product Information
- PROPYLENE GLYCOL MONOSTEARATE (CONTAINS CA. 35% MONOPALMITATE)
- PROPYLENE GLYCOL FATTY ACIDATE
- 1-(1-NAPHTHYL)-2-THIOUREA
- Propylene carbonate
- Salafibrate
- 2-(4-CHLOROPHENOXY) PROPIONIC ACID
- simfibrate
- ETHYL 2-METHYL-2-PHENOXYPROPANOATE
- METHYL 2-(4-CHLOROPHENOXY)-2-METHYLPROPANOATE
- 2-(4-Chlorophenoxy)-2-methylpropionic acid
- 1-tert-Butoxy-4-chlorobenzene