Bleomycin A5 Chemical Properties

Density 

1.1028 (rough estimate)

refractive index 

1.6700 (estimate)

pka

10.84±0.46(Predicted)

form 

Solid

color 

White to off-white

Safety Information

Toxicity

TDLo unreported in human: 192mg/kg

Bleomycin A5 Usage And Synthesis

Uses

Bleomycin A5 (Pingyangmycin) is an orally active glycopeptide antibiotics. Bleomycin A5 has a role as an antineoplastic agent, an apoptosis inducer and a bacterial metabolite[1][2].

Definition

ChEBI: A member of the class of bleomycins that is used in sclerotherapy for cervicofacial lymphatic malformations.

in vivo

References

[1] Yaowu Yang, et al. Bleomycin A5 sclerotherapy for cervicofacial lymphatic malformations. J Vasc Surg. 2011 Jan;53(1):150-5. DOI:10.1016/j.jvs.2010.07.019
[2] Lin Fu-Tian, et al. Antitumor activity and preclinical pharmacological study of pingyangmycin. Zhonghua Zhongliu Zazhi. Volume: 1. Issue: 3. Pages: 161-6. Journal; English Abstract; Article. 1979.

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