4,6-Dichloro-2-methyl-5-nitropyrimidine Chemical Properties

Boiling point:

310.4±37.0 °C(Predicted)

Density 

1.626±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

pka

-7.02±0.39(Predicted)

InChI

InChI=1S/C5H3Cl2N3O2/c1-2-8-4(6)3(10(11)12)5(7)9-2/h1H3

InChIKey

OPXGPTXSLFZVCA-UHFFFAOYSA-N

SMILES

C1(C)=NC(Cl)=C([N+]([O-])=O)C(Cl)=N1

EPA Substance Registry System

Pyrimidine, 4,6-dichloro-2-methyl-5-nitro- (13162-43-1)

4,6-Dichloro-2-methyl-5-nitropyrimidine Usage And Synthesis

Synthesis

A convenient synthesis of 4, 6-dihydro-2-methyl-pyrimidine can be obtained by cyclization reaction of acetamidine hydrochloride and diethyl malonate in the presence of sodium methoxide for a 91.2 % yield. 4, 6-Dihydro-2-methyl-5-nitropyrimidine can be achieved by nitration under the mixed acids of nitric acid, trichloroacetic acid and acetic acid in an 88.3 % yield and then the chlorination using phosphorus oxytrichloride can afford 4,6-Dichloro-2-methyl-5-nitropyrimidine with an 82.6 % yield.

4,6-Dichloro-2-methyl-5-nitropyrimidine(13162-43-1)Related Product Information

• 2-Chloro-5-chloromethylpyridine
• METSULFURON METHYL
• 2,4-Dichloro-5-nitropyrimidine
• Methyl acetate
• 4,6-Dichloropyrimidine
• Thiophanate-methyl
• 1,1-Dichlorodimethyl ether
• Tribenuron methyl
• 2-Methylpyrimidine
• Methyl salicylate
• 1,3-Dichloro-5,5-dimethylhydantoin
• Dichloroacetic acid
• Kresoxim-methyl
• Pirimiphos-methyl
• 2-Chloro-5-nitropyrimidine
• 4,6-Dichloro-5-nitropyrimidine
• Dichloromethylphenylsilane
• Dichlorodimethylsilane