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Framycetin sulphate

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Framycetin sulphate Basic information

Product Name:
Framycetin sulphate
Synonyms:
  • Framycetin Sulfate
  • NeomycinBsulfate
  • D-Streptamine, O-2,6-diamino-2,6-dideoxy-.beta.-L-idopyranosyl-(1?3)-O-.beta.-D-ribofuranosyl-(1?5)-O-2,6-diamino-2,6-dideoxy-.alpha.-D-glucopyranosyl-(1?4)-2-deoxy-, sulfate (1:3) (salt)
  • neomycin B trisulfate
  • NEOMYCIN SULPHATE B(FRAMYCETIN SULPHATE)
  • Neomycin sulphate B
  • (2R,3S,4R,5R,6R)-5-Amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2R,3R,4S,5R)-4-[(2S,3S,4S,5R,6R)-3-amino-6-(aminomethyl)-4,5-dihydroxy-oxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxy-cyclohexyl]oxy-oxane-3,4-diol sulphate
  • Framycetin sulphate
CAS:
4146-30-9
MF:
C23H48N6O17S
MW:
712.72
EINECS:
223-969-3
Product Categories:
  • Inhibitors
Mol File:
4146-30-9.mol
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Framycetin sulphate Chemical Properties

Melting point:
>160°C (dec.)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
Freely soluble in water, very slightly soluble in alcohol, practically insoluble in acetone.
form 
Solid
color 
White to Off-White
Water Solubility 
Water : 250 mg/mL (275.06 mM; Need ultrasonic)
Stability:
Hygroscopic
CAS DataBase Reference
4146-30-9(CAS DataBase Reference)
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Framycetin sulphate Usage And Synthesis

Chemical Properties

White or yellowish-white powder, hygroscopic.

Originator

Myciguent,Upjohn,US,1951

Uses

Antibacterial

Manufacturing Process

Neomycin has been produced by growing the organism, Strepromyces No. 3535, in a suitable nutrient medium under appropriate stationary or submerged aerobic (viz shaken) conditions, and then isolating and purifying the substance, e.g., by procedure of the sort described in the figure including various steps of adsorption, recovery by elution, separation from impurities, and precipitation.
Neomycin is usually used as the sulfate.

Therapeutic Function

Antibacterial

Framycetin sulphateSupplier

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