1-Cyclopropylpiperazine Chemical Properties

Boiling point:

43°C/7mm

Density 

0.94

refractive index 

1.4804

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

form 

clear liquid

pka

9.23±0.10(Predicted)

color 

Colorless to Light yellow

Safety Information

Hazard Codes 

Xi

RIDADR 

3267

HazardClass 

8

PackingGroup 

Ⅲ

HS Code 

2933599590

1-Cyclopropylpiperazine Usage And Synthesis

Uses

1-cyclopropylpiperazine is a piperazine derivative known in the literature by synonyms such as N-cyclopropylpiperazine and 4-cyclopropylpiperazine. It has been used in the preparation of some tri- and tetrasubstituted ureas with histamine H3 antagonist receptor activity, 3-amido-4- anilinoquinolines series as CSF-1R kinase inhibitors, for the synthesis of cyclopropyl amines as modulators of the histamine H3 receptor, sulfonamide compounds as cysteine protease inhibitors, N-oxides as antibacterial agents and in the treatment of the disease caused by helicobacter infection[1].

References

[1] G. Ke?an. “DFT, FT-Raman, and FT-IR investigations of 1-cyclopropylpiperazine.” Journal of Structural Chemistry 54 6 (2014): 1044–1054.

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