WILFORGINE Chemical Properties

Melting point:

211℃

Boiling point:

859.9±65.0 °C(Predicted)

Density 

1.43

solubility 

Soluble in methanol;

pka

11.59±0.70(Predicted)

form 

powder

color 

White

Water Solubility 

insoluble in water

WILFORGINE Usage And Synthesis

Uses

Wilforgine can be used as lymphocyte immunosuppression, with anti-tumor and anti-inflammatory effects, and can be used for content determination/identification/pharmacological experiments, etc.

Biological activity

Wilforgine is a bioactive sesquiterpene alkaloid in Tripterygium wilfordii Hook. F. Wilforgine can induce microstructural and ultrastructural changes in the muscles of Mythimna separata larvae, and the sites of action are proposed to be calcium receptors or channels in the muscular system.

Description

Wilforgine is a alkaloid,it from Tripterygiurn wilfordii Hook forms colourless plates from MeOH-Me2CO. It is also dextrorotatory having [α]^{25/sup>_D + 25° (Me2CO)}_。

Definition

ChEBI: A dihydroagarofuran sesquiterpenoid and pyridine alkaloid with formula C41H47NO19 originally isolated from the roots of Tripterygium wilfordii.

References

Beroza., J. Arner. Chern. Soc., 74, 1585 (1952) Beroza., ibid, 75,44 (1953)

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