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3-Bromo-2-trifluoromethylpyridine

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3-Bromo-2-trifluoromethylpyridine Basic information

Product Name:
3-Bromo-2-trifluoromethylpyridine
Synonyms:
  • 4-chloro-2-piperidin-1-ylpyridine
  • 5-(4-bromo-3-methoxythien-2-yl)-1,3,4-oxadiazol-2(3h)-one
  • 5-[(2,3-dichlorophenoxy)methyl]-1,3,4-oxadiazol-2(3h)-one
  • 5-[(e)-2-(2-chloro-3,4-dimethoxyphenyl)vinyl]-1,3,4-oxadiazol-2(3h)-one
  • 3-Bromo-2-trifluoromethylpyridine
  • 3-Bromo-2-(trifluoromethyl)pyridine
  • 4-Bromo-1H-pyrazole, N1-BOC protected
  • Halides
CAS:
590371-58-7
MF:
C6H3BrF3N
MW:
225.99
Product Categories:
  • Pyrazoles & Triazoles
  • Halides
  • Pyridines
  • Pyridine series
  • Fused Ring Systems
  • Thiophenes & Benzothiophenes
  • Thiophenes & Benzothiophenes
  • Phenyls & Phenyl-Het
  • Phenyls & Phenyl-Het
  • Pyrazoles & Triazoles
Mol File:
590371-58-7.mol
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3-Bromo-2-trifluoromethylpyridine Chemical Properties

Melting point:
34-36 °C(Solv: hexane (110-54-3))
Boiling point:
97-99 °C(Press: 35 Torr)
Density 
1.707±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
-1.80±0.22(Predicted)
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Safety Information

RIDADR 
UN2811
HazardClass 
IRRITANT
HS Code 
2933399990
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3-Bromo-2-trifluoromethylpyridine Usage And Synthesis

Uses

3-Bromo-2-(trifluoromethyl)pyridine is a fluorine-containing pyridine analogue with a bromine atom as a reactive group in its structure, which can be used in a variety of chemical reactions. It can also be used as an intermediate or raw material for organic synthesis, such as the preparation of 2-(trifluoromethyl)nicotinic acid and its derivatives.

Synthesis

3-Bromo-2-(trifluoromethyl)pyridine can be obtained by the reaction of (Trifluoromethyl)trimethylsilane with 3-Bromo-2-iodopyridine.

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