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Gonadorelin acetate

Basic information Stability Safety Supplier Related

Gonadorelin acetate Basic information

Product Name:
Gonadorelin acetate
Synonyms:
  • LUTEINIZING HORMONE RELEASING HORMONE (HUMAN) (PORCINE, RAT) 2ACOH 4H2O
  • LUTEINIZING HORMONE-RELEASING FACTOR ACETATE
  • Gonadorelllin Acetate
  • Gonadoliberin, Gonadotropin releasing hormone, LH-RH
  • Luteinizing horMone releasing horMone huMan acetate salt(LHRH)
  • Gonadorelin acetate, >=98%
  • Gonadorelni Acetate
  • N-[1-[[1-[[1-[[1-[[2-[[1-[[1-[2-[[(2-amino-2-oxoethyl)amino]-oxomethyl]-1-pyrrolidinyl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]ami
CAS:
71447-49-9
MF:
C57H79N17O15
MW:
1242.36
EINECS:
636-116-9
Product Categories:
  • API
  • peptides
  • Amino Acid Derivatives
  • Peptide
Mol File:
71447-49-9.mol
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Gonadorelin acetate Chemical Properties

storage temp. 
−20°C
solubility 
H2O: 25 mg/mL, clear, faintly yellow
form 
powder
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Safety Information

Hazard Codes 
T
Risk Statements 
60
Safety Statements 
53-45
WGK Germany 
3
RTECS 
OK6470000
10-21

MSDS

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Gonadorelin acetate Usage And Synthesis

Stability

Gonadorelin acetate is stable for at least 12 months at 24 degrees Celsius and 50 per cent relative humidity and does not degrade even under accelerated storage conditions. Similarly, the lyophilised product has shown excellent stability when stored at 24 °C at 50% relative humidity for at least 18 months. The reconstituted gonadotropin acetate is stable for at least 45 days at 24 °C or 37 °C. The reconstituted gonadotropin acetate is stable for at least 12 months at 24 °C and 50% relative humidity.

Uses

Luteinizing hormone releasing hormone human acetate salt has been used:

  • for synchronization of the ovulations
  • for pre-absorption of the anti-GnRH antibody in staining procedures
  • to study pituitary sensitivity to GnRH in presence of endocrine disrupting compound

Application

Gonadorelin acetate is widely used in the diagnosis of central precocious puberty.

Biochem/physiol Actions

Hypothalamic peptide that stimulates release of gonadotrophins from anterior pituitary, thus regulating reproductive functions.

Side effects

Gonadorelin acetate is usually considered a safe medication. However, severe anaphylactic shock may occur after intravenous administration, manifested by loss of consciousness and tonic convulsions of the arms and legs; prompt treatment with epinephrine, diphenhydramine and fluids restores vital signs within 30 minutes. Therefore, it is recommended that these drugs be administered in an environment that is capable of handling systemic reactions.

Gonadorelin acetateSupplier

Alabiochem Tech.Co., Ltd.
Tel
0512-58900862 400-0707518
Email
sales@alabiochem.com
ChemFuture PharmaTech (Jiangsu) Ltd
Tel
5108538618
Email
suger.wang@chemfuture.com
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Email
waley188@sohu.com
AdooQ BioScience, LLC
Tel
+1 (866) 930-6790
Email
info@adooq.com
ApexBio Technology LLC
Tel
+1-832-696-8203
Email
info@apexbt.com