pirodavir
pirodavir Basic information
- Product Name:
- pirodavir
- Synonyms:
-
- pirodavir
- Pirodavir, >=99%
- Ethyl 4-(2-(1-(6-methylpyridazin-3-yl)piperidin-4-yl)ethoxy)benzoate
- Ethyl p-[2-[1-(6-Methylpyridazin-3-yl)piperidin-4-yl]-ethoxy]benzoate
- Benzoic acid, 4-[2-[1-(6-Methyl-3-pyridazinyl)-4-piperidinyl]ethoxy]-, ethyl ester
- ethyl p-(2-(1-(6-Methyl-3-pyridazinyl)-4-piperidyl)ethoxy) benzoate
- R 77975
- R77975
- CAS:
- 124436-59-5
- MF:
- C21H27N3O3
- MW:
- 369.46
- Product Categories:
-
- Inhibitors
- Mol File:
- 124436-59-5.mol
pirodavir Chemical Properties
- Melting point:
- 124-125℃
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- color
- Off-White to Pale Beige
pirodavir Usage And Synthesis
Description
Pirodavir is a broad-spectrum antipicornaviral agent. It is active against 80 typed (MICs = 0.001-14.4 μg/ml) and one untyped rhinovirus strain (MIC = 0.002 μg/ml) and is active against both group A and group B serotypes. It is also active against serotypes of coxsackievirus, poliovirus, and echovirus enteroviruses (MICs = 0.018-8.5, 0.025-0.27, and 0.019-1.3 μg/ml, respectively).
Uses
Pirodavir is used to modulate lipophilicity in human rhinovirus capsid binders. It also is used in order to identify potential ativiral agents.
Uses
R 77975 is used to modulate lipophilicity in human rhinovirus capsid binders. It also is used in order to identify potential ativiral agents.
References
[1] K ANDRIES. In vitro activity of pirodavir (R 77975), a substituted phenoxy-pyridazinamine with broad-spectrum antipicornaviral activity.[J]. Antimicrobial Agents and Chemotherapy, 1992, 36 1: 100-107. DOI: 10.1128/aac.36.1.100
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