emivirine Chemical Properties

Melting point:

109.1-110.7 °C(Solv: ethanol (64-17-5); water (7732-18-5))

Density 

1.133±0.06 g/cm3(Predicted)

storage temp. 

Store at -20°C

pka

9.46±0.40(Predicted)

form 

Solid

color 

White to off-white

emivirine Usage And Synthesis

Uses

Treatment of HIV-1 infections (non-nucleoside reverse transcriptase inhibitor).

Uses

Emivirine can be used to treat disease cause by SARS-CoV-2

Definition

ChEBI: A pyrimidone that is uracil which is substituted at positions 1, 5 and 6 by ethoxymethyl, isopropyl, and benzyl groups, respectively. A non-nucleoside inhibitor of HIV-1 reverse transcriptase, emivirine was an unsuccessful experimental agent for the treatm nt of HIV.

brand name

Coactinon (Mitsubishi Chemical Corporation, Japan).

Hazard

Moderately toxic by ingestion.

Safety Profile

Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of NOx.

emivirine(149950-60-7)Related Product Information

• emivirine
• 5,6-DIMETHYLURACIL
• 6-BENZYL-3-(4-BENZYLOXY-BENZOYL)-1-ETHOXYMETHYL-5-ISOPROPYL-1H-PYRIMIDINE-2,4-DIONE