emivirine
emivirine Basic information
- Product Name:
- emivirine
- Synonyms:
-
- emivirine
- 6-benzyl-1-(ethoxymethyl)-5-isopropyluracil
- MKC 442
- 2,4(1H,3H)-Pyrimidinedione, 1-(ethoxymethyl)-5-(1-methylethyl)-6-(phenylmethyl)-
- 1-(Ethoxymethyl)-6-benzyl-5-isopropyluracil
- DRG 0302
- DRG0302
- DRG-0302
- CAS:
- 149950-60-7
- MF:
- C17H22N2O3
- MW:
- 302.37
- Mol File:
- 149950-60-7.mol
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emivirine Chemical Properties
- Melting point:
- 109.1-110.7 °C(Solv: ethanol (64-17-5); water (7732-18-5))
- Density
- 1.133±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- pka
- 9.46±0.40(Predicted)
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emivirine Usage And Synthesis
Uses
Treatment of HIV-1 infections (non-nucleoside reverse transcriptase inhibitor).
Uses
Emivirine can be used to treat disease cause by SARS-CoV-2
Definition
ChEBI: A pyrimidone that is uracil which is substituted at positions 1, 5 and 6 by ethoxymethyl, isopropyl, and benzyl groups, respectively. A non-nucleoside inhibitor of HIV-1 reverse transcriptase, emivirine was an unsuccessful experimental agent for the treatm nt of HIV.
brand name
Coactinon (Mitsubishi Chemical Corporation, Japan).
Hazard
Moderately toxic by ingestion.
Safety Profile
Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of NOx.
emivirineSupplier
Shanghai Tachizaki Biomedical Research Center Gold
- Tel
- 18014399201
- sales@chemlab-tachizaki.com
LGM Pharma
- Tel
- 1-(800)-881-8210
- inquiries@lgmpharma.com
Beijing HuaMeiHuLiBiological Chemical
- Tel
- 010-56205725
- waley188@sohu.com
Shanghai Witofly Chemical Co.,Ltd
- Tel
- sales@witofly.com
Shanghai EFE Biological Technology Co., Ltd.
- Tel
- 021-65675885 18964387627
- info@efebio.com