3-METHYLTHIOPHENE-2-CARBONITRILE Chemical Properties

Boiling point:

91-93°C 12mm

refractive index 

1.5530

Flash point:

91-93°C/12mm

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

BRN 

5495606

CAS DataBase Reference

55406-13-8(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

20/21/22

Safety Statements 

36/37/39

RIDADR 

3276

Hazard Note 

Irritant

HazardClass 

6.1

PackingGroup 

III

HS Code 

2934999090

MSDS

• Language:English Provider:ALFA

3-METHYLTHIOPHENE-2-CARBONITRILE Usage And Synthesis

Preparation

3-Methylthiophene-2-carbonitrile synthesis: 3-Methyl-2-thiophenecarboxamide (18.6 g, 0.13 mol) was mixed with an excess of POCl3, and the mixture heated at reflux temperature for 2 h. The excess POCl3 was removed under vacuum and the residue dissolved in 500 mL of 1,2-dichloroethane, washed (carefully!) with water, then brine, and the solvent removed to give 23 g of crude 3-methyl-2-thiophenecarbonitrile. This material was passed through a plug of silica gel with CH2Cl2 and the solvent evaporated to give 16.2 g (100%) of as a light tan oil: 1H NMR (CDCl3) d 7.4 (d, J=4.8 Hz, 1H), 6.9 (d, J=5.4 Hz, 1H), 2.4 ppm (s, 3H); 97% pure by HPLC area %.

3-METHYLTHIOPHENE-2-CARBONITRILE(55406-13-8)Related Product Information

• 3-[(4-FORMYLPHENOXY)METHYL]THIOPHENE-2-CARBONITRILE
• 3,4-Diphenylthiophene-2,5-dicarbonitrile, 97%
• 6,6-DIMETHYL-3-(METHYLTHIO)-4-OXO-4,5,6,7-TETRAHYDROBENZO[C]THIOPHENE-1-CARBONITRILE
• 3,4-DIMETHYLTHIOPHENE-2,5-DICARBONITRILE
• 5-CYANO-3,4-DIPHENYLTHIOPHENE-2-CARBOXAMIDE
• 3-METHYLTHIOPHENE-2-CARBONITRILE
• 2-(NITROANILINO)-5-METHYLTHIOPHENE-3-CARBONITRILE
• 2-AMINO-5-METHYLTHIOPHENE-3-CARBONITRILE
• ETHYL 5-CYANO-3,4-DIMETHYLTHIENO[2,3-B]THIOPHENE-2-CARBOXYLATE
• 5-ACETYL-3,4-DIMETHYLTHIENO[2,3-B]THIOPHENE-2-CARBONITRILE
• 5-CYANO-3,4-DI(4-METHOXYPHENYL)THIOPHENE-2-CARBOXAMIDE
• 5-CYANO-N-(([(2-FLUOROBENZYL)OXY]IMINO)METHYL)-3-METHYL-4-PHENYL-2-THIOPHENECARBOXAMIDE
• 3-(ETHYLTHIO)-6,6-DIMETHYL-4-OXO-4,5,6,7-TETRAHYDROBENZO[C]THIOPHENE-1-CARBONITRILE
• 5-CYANO-3,4-DIMETHYLTHIOPHENE-2-CARBOXAMIDE
• 2-AMINO-4-(4-FLUOROPHENYL)-5-METHYLTHIOPHENE-3-CARBONITRILE
• 2-AMINO-4-(4-METHOXYPHENYL)-5-METHYLTHIOPHENE-3-CARBONITRILE
• 2-AMINO-4-ETHYL-5-METHYLTHIOPHENE-3-CARBONITRILE
• 5-Methylthiophene-2-carbonitrile 95%,5-methylthiophene-2-carbonitrile