1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid Chemical Properties

Melting point:

289°C(lit.)

Boiling point:

434.2±45.0 °C(Predicted)

Density 

1.630±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

solubility 

DMSO

form 

Solid

pka

6.36±0.41(Predicted)

color 

Off-White

InChI

InChI=1S/C13H9F2NO3/c14-9-3-7-11(4-10(9)15)16(6-1-2-6)5-8(12(7)17)13(18)19/h3-6H,1-2H2,(H,18,19)

InChIKey

KNEXGVPHPGXAGF-UHFFFAOYSA-N

SMILES

N1(C2CC2)C2=C(C=C(F)C(F)=C2)C(=O)C(C(O)=O)=C1

Safety Information

Hazard Codes 

Xn

Risk Statements 

62-52/53

Safety Statements 

22-36/37-61

HS Code 

2933.49.7000

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid Usage And Synthesis

Uses

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid is a metabolite of Moxifloxacin (M745000) and is used in the synthesis of chiral aminopiperidinyl quinolones as potent antibacterial agents against resistant pathogens.

General Description

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid and 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3 -Carboxylic Acid has a similar structure; the difference lies in the number of substituted fluorine atoms. They could be formed as an intermediate during the synthesis of ciprofloxacin hydrochloride, a fluorinated quinolone antibacterial drug.

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid(93107-30-3)Related Product Information

• Perfluoro-1-iodohexane
• METHYL 1-N-CYCLOPROPYL-6,7-DIFLUORO-8-METHYL-5-NITRO-4-OXO-1,2-DIHYDRO-QUINOLINE-3-CARBOXYLATE
• 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid ethyl ester
• 1-CYCLOPROPYL-6,7-DIFLUORO-8-DIFLUOROMETHOXY-4-OXO-3-QUINOLINE CARBOXYLIC ACID
• ETHYL 1-CYCLOPROPYL-5,6,7,8-TETRAFLUORO-4(1H)-OXOQUINOLINE-3-CARBOXYLATE
• 1-CYCLOPROPYL-5-NITRO-6,7,8-TRIFLUORO-1,4-DIHYDRO-4-OXO-3- QUINOLINECARBOXYLIC ACID ETHYL ESTER
• 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid
• AKOS 1130
• 5-AMINO-1-CYCLOPROPYL-6,7-DIFLUORO-1,4-DIHYDRO-8-METHYL-4-OXO-3-QUINOLINECARBOCYLIC ACID
• 1-CYCLOPROPYL-5-AMIDO-6,7,8-TRIFLUORO-1,4-DIHYDRO-4-OXO-3- QUINOLINECARBOXYLIC ACID ETHYL ESTER
• ethyl 8-chloro-1-cyclopropyl-6,7-difluoro-1,4-dihydroquinoline-4-oxo-3-carboxyla
• 1-CYCLOPROPYL-6,7-DIFLUORO-5-METHYL-4-OXO-3-QUINOLINE CARBOXYLIC ACID
• 1-Cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxoq
• 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid