Asiatic acid
Asiatic acid Basic information
- Product Name:
- Asiatic acid
- Synonyms:
-
- 2,3,23-TRIHYDROXY-12-URSEN-28-OIC ACID
- (1s,2r,4as,6ar,6as,6br,8ar,9s,10s,11r,12as,14br)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1h-picene-4a-carboxylic acid
- ASIATIC ACID
- URS-12-EN-28-OIC ACID, 2,3,23-TRIHYDROXY-, (2A,3B,4A)-
- Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, (2.alpha.,3.beta.,4.alpha.)-
- ASIATIC ACID(P)
- Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, (2α,3β,4α)-
- ASIATICACID:URS-12-EN-28-OICACID, 2,3,23-TRIHYDROXY-, (2A,3B,4A)-,
- CAS:
- 464-92-6
- MF:
- C30H48O5
- MW:
- 488.7
- EINECS:
- 482-720-9
- Product Categories:
-
- Inhibitors
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Pentacyclic Triterpenes
- Steroids
- The group of Asiaticoside
- C13 to C42+
- Carbonyl Compounds
- Carboxylic Acids
- Antineoplastic
- 464-92-6
- API
- Mol File:
- 464-92-6.mol
Asiatic acid Chemical Properties
- Melting point:
- 325-330 °C(lit.)
- Boiling point:
- 609.4±55.0 °C(Predicted)
- Density
- 1.18±0.1 g/cm3(Predicted)
- RTECS
- YU9580000
- storage temp.
- 2-8°C
- solubility
- methanol: soluble1mg/mL, clear, colorless
- form
- powder
- pka
- 4.66±0.70(Predicted)
- color
- white
- Water Solubility
- Soluble in dimethyl sulfoxide, ethanol and dimethylformamide. Sparingly soluble in water
- InChIKey
- JXSVIVRDWWRQRT-UYDOISQJSA-N
- LogP
- 5.748 (est)
- CAS DataBase Reference
- 464-92-6(CAS DataBase Reference)
Safety Information
- Hazard Codes
- Xi
- WGK Germany
- 3
- HS Code
- 29181990
- Hazardous Substances Data
- 464-92-6(Hazardous Substances Data)
MSDS
- Language:English Provider:SigmaAldrich
Asiatic acid Usage And Synthesis
Uses
wound healing, experimental carcinogen
Uses
Asiatic Acid is a terpenoid with an ursane skeleton isolated from Centella asiatica. Asiatic Acid is a neuroprotectant and induces of apoptosis in HepG2 human hepatoma cells.
Uses
Asiatic acid is commonly used in wound healing. Asiatic acid has antioxidant, anti-inflammatory and neuroprotective properties. It is a starting material for asiatic acid derivative synthesis for use as anticancer agents, glycogen phosphorylase inhibitors and and hepatoprotectants.
Definition
ChEBI: A pentacyclic triterpenoid that is ursane substituted by a carboxy group at position 28 and hydroxy groups at positions 2, 3 and 23 (the 2alpha,3beta stereoisomer). It is isolated from Symplocos lancifolia and Vateria indica and exhibits anti-angiogenic activity.
General Description
Asiatic acid is a naturally occurring pentacyclic triterpenoid, obtained from Centella asiatica.
Biochem/physiol Actions
Asiatic acid is commonly used in wound healing. Asiatic acid has antioxidant, anti-inflammatory and neuroprotective properties.
target
TNF-α | IFN-γ | IL Receptor | Caspase | p21 | NOS | NADPH-oxidase | NO | HMG-CoA reductase | COX
Asiatic acidSupplier
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- 029-029-86629612 18202932191
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- 025-84430028 13815430202
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Asiatic acid(464-92-6)Related Product Information
- Shikimic acid
- Calcium oxalate
- Ammonium oxalate monohydrate
- Dimethyl oxalate
- Ferrous oxalate
- Ethyl 2-(Chlorosulfonyl)acetate
- Hyaluronic acid
- Citric acid
- Folic acid
- Ascoric Acid
- Madecassic acid
- niga-ichigoside F1
- Asiatic acid
- Centella asiatica whole plant
- ASIATIC ACID 95%
- 2,3,23-TRI(ACETYLOXY)-(2ALPHA,3BETA,4ALPHA)-URS-12-EN-28-OIC ACID
- ASIATIC ACID(RG)
- 2,3,23-TRI(ACETYLOXY)-(2ALPHA,3BETA,4ALPHA)-URS-12-EN-28-OIC ACID METHYL ESTER