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Asiatic acid

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Asiatic acid Basic information

Product Name:
Asiatic acid
Synonyms:
  • 2,3,23-TRIHYDROXY-12-URSEN-28-OIC ACID
  • (1s,2r,4as,6ar,6as,6br,8ar,9s,10s,11r,12as,14br)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1h-picene-4a-carboxylic acid
  • ASIATIC ACID
  • URS-12-EN-28-OIC ACID, 2,3,23-TRIHYDROXY-, (2A,3B,4A)-
  • Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, (2.alpha.,3.beta.,4.alpha.)-
  • ASIATIC ACID(P)
  • Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, (2α,3β,4α)-
  • ASIATICACID:URS-12-EN-28-OICACID, 2,3,23-TRIHYDROXY-, (2A,3B,4A)-,
CAS:
464-92-6
MF:
C30H48O5
MW:
488.7
EINECS:
482-720-9
Product Categories:
  • Inhibitors
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Pentacyclic Triterpenes
  • Steroids
  • The group of Asiaticoside
  • C13 to C42+
  • Carbonyl Compounds
  • Carboxylic Acids
  • Antineoplastic
  • 464-92-6
  • API
Mol File:
464-92-6.mol
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Asiatic acid Chemical Properties

Melting point:
325-330 °C(lit.)
Boiling point:
609.4±55.0 °C(Predicted)
Density 
1.18±0.1 g/cm3(Predicted)
RTECS 
YU9580000
storage temp. 
2-8°C
solubility 
methanol: soluble1mg/mL, clear, colorless
form 
powder
pka
4.66±0.70(Predicted)
color 
white
Water Solubility 
Soluble in dimethyl sulfoxide, ethanol and dimethylformamide. Sparingly soluble in water
InChIKey
JXSVIVRDWWRQRT-UYDOISQJSA-N
LogP
5.748 (est)
CAS DataBase Reference
464-92-6(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
WGK Germany 
3
HS Code 
29181990
Hazardous Substances Data
464-92-6(Hazardous Substances Data)

MSDS

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Asiatic acid Usage And Synthesis

Uses

wound healing, experimental carcinogen

Uses

Asiatic Acid is a terpenoid with an ursane skeleton isolated from Centella asiatica. Asiatic Acid is a neuroprotectant and induces of apoptosis in HepG2 human hepatoma cells.

Uses

Asiatic acid is commonly used in wound healing. Asiatic acid has antioxidant, anti-inflammatory and neuroprotective properties. It is a starting material for asiatic acid derivative synthesis for use as anticancer agents, glycogen phosphorylase inhibitors and and hepatoprotectants.

Definition

ChEBI: A pentacyclic triterpenoid that is ursane substituted by a carboxy group at position 28 and hydroxy groups at positions 2, 3 and 23 (the 2alpha,3beta stereoisomer). It is isolated from Symplocos lancifolia and Vateria indica and exhibits anti-angiogenic activity.

General Description

Asiatic acid is a naturally occurring pentacyclic triterpenoid, obtained from Centella asiatica.

Biochem/physiol Actions

Asiatic acid is commonly used in wound healing. Asiatic acid has antioxidant, anti-inflammatory and neuroprotective properties.

target

TNF-α | IFN-γ | IL Receptor | Caspase | p21 | NOS | NADPH-oxidase | NO | HMG-CoA reductase | COX

Asiatic acidSupplier

Shaanxi Pioneer Biotech Co., Ltd. Gold
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Nanjing Spring & Autumn Biological Engineering Co., Ltd. Gold
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025-84430028 13815430202
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J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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INTATRADE GmbH
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3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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