ChemicalBook > Product Catalog > Biochemical Engineering > Amino Acids and Derivatives > Proline derivatives > (2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate
(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate
(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate Basic information
- Product Name:
- (2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate
- Synonyms:
-
- (2R,4R)-4-Hydroxy-1,2-pyrrolidinedicarboxylicacid 1-(1,1-dimethylethyl) 2-methyl ester
- (2R,4R)-1-tert-butyl 2-Methyl 4-hydroxypyrrolidine-1,2-dicarboxy
- (2R,4R)-1-tert-butyl 2-Methyl 4-hydro×ypyrrolidine-1,2-dicarbo×ylate
- Boc-Cis-D-Hyp-OMe
- Methy cis-1-Boc-4-hydroxy-D-prolinate
- Methyl cis-Boc-4-hydroxy-D-prolinate
- 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-methyl ester, (2R,4R)-
- 1-tert-butyl 2-methyl (2R,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
- CAS:
- 114676-69-6
- MF:
- C11H19NO5
- MW:
- 245.27
- EINECS:
- 675-952-9
- Mol File:
- 114676-69-6.mol
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(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate Chemical Properties
- Melting point:
- 76 °C
- Boiling point:
- 335.2±42.0 °C(Predicted)
- alpha
- 63° (C=1,EtOH)
- Density
- 1.216±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- form
- Powder
- pka
- 14.27±0.40(Predicted)
- color
- White
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(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate Usage And Synthesis
Uses
(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate (N-Boc-cis-4-hydroxy-D-proline methyl ester) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). (2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate Supplier
ZhengZhou Yimi Pharma R&D Co.,LTD. Gold
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- 15393710992
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Shanghai Xinxin Pharmaceutical Technology Co., Ltd. Gold
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- 13671725141
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Henan Alfachem Co.,Ltd. Gold
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- 0371-0371-55051623 18137891487
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PharmaBlock Sciences (Nanjing),Inc.
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- 400-0255188 4000255188
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Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel
- 4006608290; 18621169109
- market03@meryer.com
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(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate (114676-69-6)Related Product Information
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- (2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate
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