3-Bromofluorobenzene Chemical Properties

Melting point:

-8°C

Boiling point:

149-151 °C(lit.)

Density 

1.567 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.526(lit.)

Flash point:

102 °F

storage temp. 

Sealed in dry,Room Temperature

solubility 

0.4g/l

form 

Liquid

Specific Gravity

1.567

color 

Clear colorless to light yellow

Water Solubility 

insoluble

BRN 

1853969

InChIKey

QDFKKJYEIFBEFC-UHFFFAOYSA-N

CAS DataBase Reference

1073-06-9(CAS DataBase Reference)

NIST Chemistry Reference

Benzene, 1-bromo-3-fluoro-(1073-06-9)

EPA Substance Registry System

Benzene, 1-bromo-3-fluoro- (1073-06-9)

Safety Information

Hazard Codes 

Xn,F,Xi

Risk Statements 

10-22-36/38-36/37/38-20/21/22

Safety Statements 

26-36-37/39-16

RIDADR 

UN 1993 3/PG 3

WGK Germany 

2

RTECS 

DA1225000

Hazard Note 

Flammable/Irritant

TSCA 

Yes

HazardClass 

3

PackingGroup 

III

HS Code 

29036990

MSDS

• Language:English Provider:1-Bromo-3-fluorobenzene
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

3-Bromofluorobenzene Usage And Synthesis

Chemical Properties

Clearcolourlesstolightyellowliqui

Uses

Intermediates of Liquid Crystals

Synthesis

The general procedure for the synthesis of m-bromofluorobenzene from the compound (CAS: 1430342-19-0) is as follows: a mixture of diaryliodonium salt (0.5 mmol), methylene halide (0.75 mmol) and acetonitrile (1 mL) was added to a 10 mL reaction tube and heated at 80 °C for 2 h with vigorous stirring. After completion of the reaction (monitored by TLC or GC), the reaction mixture was cooled to room temperature and 5 mL of water was added. After stirring for 10 min, the product was extracted with ethyl acetate (3 x 10 mL). The organic layers were combined, washed with water and dried with anhydrous sodium sulfate. The solvent was evaporated under reduced pressure to give the crude product. The crude product was purified by silica gel column chromatography using petroleum ether and ethyl acetate as eluents to give purified m-bromofluorobenzene. The structure of the product was confirmed by 1H NMR and 13C NMR.

References

[1] Letters in Organic Chemistry, 2013, vol. 10, # 8, p. 541 - 548

3-Bromofluorobenzene(1073-06-9)Related Product Information

• Fluorobenzene
• 3-Bromoanisole
• 3-Bromophenol
• 1,3-Difluorobenzene
• 4-Fluorobenzaldehyde
• 2-Bromobenzonitrile
• Transfluthrin
• 4'-Bromopropiophenone
• Florfenicol
• 3-Bromobenzyl bromide
• 3-Bromotoluene
• 1,3-Dibromobenzene
• 3-Bromobenzoic acid
• 3-Nitrobenzoic acid
• 3-Trifluoromethylphenol
• m-Toluic acid
• 1,3-Dimethoxybenzene
• 3-Nitroacetophenone