DODECYL PHOSPHOCHOLINE Chemical Properties

Melting point:

224-226 °C

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

solubility 

DMF: 16 mg/ml; DMSO: 16 mg/ml; Ethanol: 15 mg/ml; PBS (pH 7.2): 25 mg/ml

form 

A crystalline solid

color 

White to off-white

InChI

InChI=1S/C17H38NO4P/c1-5-6-7-8-9-10-11-12-13-14-16-21-23(19,20)22-17-15-18(2,3)4/h5-17H2,1-4H3

InChIKey

QBHFVMDLPTZDOI-UHFFFAOYSA-N

SMILES

O(CC[N+](C)(C)C)P([O-])(=O)OCCCCCCCCCCCC

DODECYL PHOSPHOCHOLINE Usage And Synthesis

Chemical Properties

mp 251-252°C

Uses

n-Dodecylphosphocholine (unlabelled) (CAS# 29557-51-5) is a useful research compound. This compound can be used to produce large amounts of function membrane of the protein, hERG.

Definition

ChEBI: Dodecylphosphocholine is a phosphocholine that is the monododecyl ester of phosphocholine It has a role as a detergent.

Biological Activity

MAPCHOTM-12 or n-dodecylphosphocholine in combination with 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is used for membrane-mimetic bicelle system for orientation based studies in membrane proteins. It provides a zwitterionic surface in the membrane micelle structure.

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