Tiflucarbine
Tiflucarbine Basic information
- Product Name:
- Tiflucarbine
- Synonyms:
-
- Tiflucarbine
- 9-Ethyl-4-fluoro-7,8,9,10-tetrahydro-1-methyl-6H-pyrido[4,3-b]thieno[3,2-e]indole
- BAY-p-4495
- CAS:
- 89875-86-5
- MW:
- 0
- Mol File:
- 89875-86-5.mol
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Tiflucarbine Usage And Synthesis
Uses
Tiflucarbine (BAY-P 4495) is a tetrahydrothieno-7-carboline derivative. Tiflucarbine is a potent antidepressant agent that binds at central serotonin (5-HT) binding sites. Tiflucarbine is a nonselective 5-HT (5-HT1 and 5-HT2) agonist[1][2].
References
[1] Schmidt BH, et al. Evidence for a specific recognition site for tiflucarbine on calmodulin. Eur J Pharmacol. 1990 Dec 15;189(6):411-8. DOI:10.1016/0922-4106(90)90039-z
[2] Glennon RA, et al. Stimulus properties of tiflucarbine: a novel antidepressant agent. Pharmacol Biochem Behav. 1990 Dec;37(4):769-71. DOI:10.1016/0091-3057(90)90561-u
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