dl-3-hydroxynorvaline Chemical Properties

Melting point:

231.2℃

Boiling point:

328.4±32.0 °C(Predicted)

Density 

1.237±0.06 g/cm3(Predicted)

storage temp. 

-20°C

pka

2.39±0.24(Predicted)

BRN 

1722350

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

dl-3-hydroxynorvaline Usage And Synthesis

Definition

ChEBI: A non-proteinogenic amino-acid derivative that is norvaline (2-aminopentanoic acid) in which a hydrogen at position 3 is replaced by a hydroxy group.

Biochem/physiol Actions

3-Hydroxynorvaline (HNV) is a microbial, α amino acid threonine analogue which has antiviral activity (herpes virus) and is toxic to mammalian cells (embryotoxic and teratogenic) presumably via incorporation into proteins. 3-Hydroxynorvaline may be used as an unnatural amino acid to study the fidelity of protein translation at the level of acyl-tRNA editing. 3-Hydroxynorvaline may also be used to study enzymes and molecules involved in threonine metabolism.

dl-3-hydroxynorvaline(2280-42-4)Related Product Information

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