2-amino-4-(2-amino-3-hydroxy-phenyl)-4-oxo-butanoic acid Chemical Properties

Melting point:

187.5°C (rough estimate)

Boiling point:

365.61°C (rough estimate)

Density 

1.2995 (rough estimate)

refractive index 

1.6620 (estimate)

storage temp. 

2-8°C

pka

2.16±0.23(Predicted)

2-amino-4-(2-amino-3-hydroxy-phenyl)-4-oxo-butanoic acid Usage And Synthesis

Uses

(S)-2-Amino-4-(2-amino-3-hydroxyphenyl)-4-oxobutanoic acid (CAS# 606-14-4) is metabolite of L-tryptophan. 3-Hydroxy L-kynurenine may be an endogenous oxidative stress generator and a potential endogenous neurotoxin. It is also used by biological study and diagnostic use in biomarker composition for predicting prognosis of diabetes mellitus after bariatric surgery.

Definition

ChEBI: 3-hydroxy-L-kynurenine is a 3-hydroxykynurenine. It has a role as a Saccharomyces cerevisiae metabolite and a mouse metabolite. It is a tautomer of a 3-hydroxy-L-kynurenine zwitterion.

2-amino-4-(2-amino-3-hydroxy-phenyl)-4-oxo-butanoic acid(606-14-4)Related Product Information

• L-KYNURENINE
• 2-(3-INDOLYLMETHYL)-L-TRYPTOPHAN
• 3-[(4-hydroxyphenyl)methyl]piperazine-2,5-dione
• 2-(1H-indol-3-yl)acetaldehyde
• 5-Hydroxytryptophan
• Tryptophan Impurity 1（Tryptophan EP Impurity A）
• HARMANE-1,2,3,4-TETRAHYDRO-3-CARBOXYLIC ACID
• 3-(phenylamino)alanine
• 2-Hydroxy-DL-tryptophan
• N-Acetyl-L-tryptophan
• DL-METHIONINE SULFOXIDE
• L-2-hydroxyTryptophan hydrochloride
• Fmoc-Trp(Boc)-OH
• 5-(1H-indol-3-ylmethyl)-3-prop-2-enyl-2-sulfanylideneimidazolidin-4-one
• Tryptophan Impurity 3
• CYCLO(-GLY-GLN)
• D-2-AMINO-3-(5-HYDROXYINDOLYL)PROPIONIC ACID
• 3-ethyl-5-(1H-indol-3-ylmethyl)-2-sulfanylideneimidazolidin-4-one