2-Piperidineethanol Chemical Properties

Melting point:

38-40 °C (lit.)

Boiling point:

234 °C (lit.)

Density 

1.01

vapor pressure 

0.75-13.04Pa at 20-50℃

refractive index 

1.4749 (estimate)

Flash point:

>230 °F

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

Chloroform, Methanol

form 

Crystalline Low Melting Solid

pka

15.15±0.10(Predicted)

color 

White to pale yellow

Odor

Mild, sweet, nauseating-floral, warm-herbaceous odor of moderate tenacity.

Water Solubility 

soluble

InChIKey

PTHDBHDZSMGHKF-UHFFFAOYSA-N

LogP

0.263 at 22.5℃

Surface tension

60.75mN/m at 1g/L and 20℃

CAS DataBase Reference

1484-84-0(CAS DataBase Reference)

NIST Chemistry Reference

2-(2-Hydroxyethyl)piperidine(1484-84-0)

EPA Substance Registry System

2-Piperidineethanol (1484-84-0)

Safety Information

Hazard Codes 

C,Xi

Risk Statements 

20/21/22-34-36/37/38

Safety Statements 

26-27-28-36/37/39-45-24/25

RIDADR 

UN 3263 8/PG 2

WGK Germany 

3

HazardClass 

8

PackingGroup 

III

HS Code 

29339900

MSDS

• Language:English Provider:2-(2-Hydroxyethyl)piperidine
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich

2-Piperidineethanol Usage And Synthesis

Chemical Properties

Off-White Solid

Uses

Reactant for syntehsis of:
Spiroimidazolidinone NPC1L1 inhibitors
P2Y12 antagonists for inhibition of platelet aggregation
Cyclin-dependent kinase inhibitors
Anti-HIV agents
Tetraponerine analogs

Reactant for cyclization of secondary homoallylic amines

Uses

2-Piperidineethanol is useful in preparation of a novel class of pyrazolopyrimidines as inhibitors of protein and checkpoint kinases useful in treatment and prophylaxis of HCV infection and other diseases such as cancer.

Uses

Heterocyclic compound used in cosmetic compositions.

Synthesis

2-Piperidineethanol is produced from 2-alpha-Pyridylethanol by hydrogenation.

2-Piperidineethanol(1484-84-0)Related Product Information

• Sodium isethionate
• Haloperidol
• 2-HYDROXYETHYLUREA
• Hydroxyethyl Cellulose
• Diphenoxylate
• Ethanol
• 2-(Ethylamino)ethanol
• 2-(2-Aminoethylamino)ethanol
• Hydroxyethyl starch
• 2-(METHYLSULFONYL)ETHANOL
• 1-PIPERIDINEETHANOL,N-PIPERIDINEETHANOL,1-Piperidineethanol/1-(2-Hydroxyethyl)Piperidine/2-(1-Piperidino)Ethanol
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• PIPERIDINEETHANOL(4-)
• CONDELPHINE
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• Lobeline
• SWAINSONINE
• Methylphenidate hydrochloride