9-methoxycamptothecin Chemical Properties

Melting point:

254-255℃

Boiling point:

773.1±60.0 °C(Predicted)

Density 

1.50

storage temp. 

4°C, protect from light

solubility 

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

form 

Cryst.

pka

11.21±0.20(Predicted)

9-methoxycamptothecin Usage And Synthesis

Description

A minor constituent of Mappia foetida Miers. The alkaloid yields pale yellow crystals when purified from CHC13-MeOH. It is laevorotatory with [α]²⁴_D - 77.5° (c 1.0, pyridine). The structure has been established by spectroscopic methods.

Uses

10-Methoxycamptothecin is a Camptothecin (C175150) derivative used in the treatment of cancers. Used in the treatment of hyperproliferative diseases.

Uses

9-Methoxycamptothecin is an alkaloid derivative of Camptothecin (C175150) derivative used in the treatment of cancers. Camptothecin is a potent anti-cancer agent.

References

Govindachari, Viswanathan., Phytochem., 11, 3529 (1972)
Govindachari, Viswanathan.,Ind. J. Chem., 10,453 (1972)

9-methoxycamptothecin(19685-10-0)Related Product Information

• VERATRINE
• 2-[2-(Methylamino)benzoyl]-3,4-dihydro-β-carboline-1(2H)-one
• Topotecan hydrochloride
• 10-HydroxycaMptothecin acetate
• menisdaurin
• Daurinoline
• (+)-Camptothecin
• RUBITECAN
• 10-Hydroxycamptothecin
• veratramine
• (4S)-4-Ethyl-4-hydroxy-10-methoxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
• Irinotecan hydrochloride
• daurisoline
• 9-amino-20-camptothecin
• L-Hyoscyamine
• Xanthiazone
• Xanthiside
• VERATRIDINE