N-succinimidyl-4-((iodoacetyl)amino)benzoate Chemical Properties

Melting point:

19-7-200°C (dec.)

Density 

1.87±0.1 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

Acetontrile (Slightly), DMSO (Slightly)

form 

Solid

pka

12.16±0.70(Predicted)

color 

Pale Yellow

Safety Information

HS Code 

2921490090

N-succinimidyl-4-((iodoacetyl)amino)benzoate Usage And Synthesis

Chemical Properties

Pale Yellow Solid

Uses

A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. Spacer Arm: 10.6 Angstroms

Uses

A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. Spacer Arm: 10.6 Angstroms

General Description

SIAB is an amine- and sulfhydryl-reactive heterobifunctional crosslinker and Sulfo-SIAB is its water-soluble analog. These crosslinkers contain an amine-reactive N-hydroxysuccimide (NHS) ester and a sulfhydryl-reactive iodoacetyl group, and are often used for preparing enzyme conjugates or immunotoxins. Water-soluble and water-insoluble forms of NHS esters have essentially identical reactivity. Sulfo-SIAB is supplied as a sodium salt and is water-soluble to ~10mM. SIAB must be first dissolved in an organic solvent, such as DMSO or DMF, and then added to the aqueous reaction mixture. SIAB is lipophilic, membrane-permeable and does not possess a charged group.

N-succinimidyl-4-((iodoacetyl)amino)benzoate(72252-96-1)Related Product Information

• IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER
• N-Succinimidyl 4-(4-maleimidophenyl)butyrate
• p-Acetylamino benzoic acid
• 4-Acetamidobenzaldehyde
• N-succinimidyl-4-((iodoacetyl)amino)benzoate
• 2-Iodoacetamide
• N-Hydroxymaleimide