cycloheterophyllin
cycloheterophyllin Basic information
- Product Name:
- cycloheterophyllin
- Synonyms:
-
- cycloheterophyllin
- (+)-2,3,8-Trihydroxy-11,11-dimethyl-13-(3-methyl-2-butenyl)-6-(2-methyl-1-propenyl)-6H,7H,11H-bis[1]benzopyrano[4,3-b:6',7'-e]pyran-7-one
- 6H,7H,11H-Bis[1]benzopyrano[4,3-b:6',7'-e]pyran-7-one, 2,3,8-trihydroxy-11,11-dimethyl-13-(3-methyl-2-buten-1-yl)-6-(2-methyl-1-propen-1-yl)-, (+)-
- CAS:
- 36545-53-6
- MF:
- C30H30O7
- MW:
- 502.55
- Mol File:
- 36545-53-6.mol
cycloheterophyllin Chemical Properties
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- powder
- color
- Yellow
- LogP
- 8.120 (est)
cycloheterophyllin Usage And Synthesis
Description
Cycloheterophyllin exerts a concentration-dependent inhibition of neutrophil cytosolic protein kinase C (PKC) and rat brain PKC by the O2- generation in rat neutrophils, but has no effect on porcine heart protein kinase A (PKA). Cycloheterophyllin has an antioxidant effect and can effectively scavenge free radicals. 3. Cycloheterophyllin is a photoprotective agent that inhibits ultraviolet A (UVA)-induced oxidative stress and damage, and could be used in the research on and prevention of skin photoaging. 4. Cycloheterophyllin shows strong inhibition of arachidonic acid (AA)-induced platelet aggregation, due to an inhibitory effect on cyclooxygenase.
Definition
ChEBI: Cycloheterophyllin is an extended flavonoid.
target
PKA | PKC | NADPH-oxidase | NF-kB | Caspase | MAPK
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