macrocalin A
macrocalin A Basic information
- Product Name:
- macrocalin A
- Synonyms:
-
- (-)-Isodocarpin
- (10bS)-1,2,3,3aβ,8,9,10,10aα,13,13aβ-Decahydro-13β-hydroxy-1,1-dimethyl-7-methylene-5H-5aβ,8β-methanocyclohepta[c]furo[3,4-e][1]benzopyran-5,6(7H)-dione
- 13-Deoxyenmein
- Isodocarpin
- 7H-5a,8-Methano-11H-cyclohepta[c]furo[3,4-e][1]benzopyran-5,6-dione, decahydro-13-hydroxy-1,1-dimethyl-7-methylene-, (3aS,5aS,8R,10aS,10bS,13R,13aR)-
- CAS:
- 10391-08-9
- MF:
- C20H26O5
- MW:
- 346.42
- Mol File:
- 10391-08-9.mol
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macrocalin A Chemical Properties
- Melting point:
- 270-273℃
- Boiling point:
- 568.7±50.0 °C(Predicted)
- Density
- 1.30±0.1 g/cm3(Predicted)
- pka
- 12.83±0.40(Predicted)
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macrocalin A Usage And Synthesis
Uses
(-)-Isodocarpin (Isodocarpin), a diterpenoid, is a potent melanogenesis inhibitor with an IC50 of 0.19 μM in B16 4A5 cells. (-)-Isodocarpin inhibits the expression of tyrosinase, tyrosine-related protein (TRP)-1, and TRP-2 mRNA[1].
References
[1] Yoshiaki Manse, et al. Melanogenesis Inhibitory Activity of Diterpenoid and Triterpenoid Constituents from the Aerial Part of Isodon trichocarpus. Natural Product Communications. August 1, 2017.
macrocalin ASupplier
BioBioPha Co., Ltd.
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- 0871-65217109 13211707573;
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Wuxi Zhongkun Biochemical Technology Co., Ltd.
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- 0510-85629785 18013409632
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ALB Technology Limited
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- 702-983-3769
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- 18607101326 15172504745
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EMMX Biotechnology LLC
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- 888-539-0666
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