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16-epi-isositsirikine

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16-epi-isositsirikine Basic information

Product Name:
16-epi-isositsirikine
Synonyms:
  • 16-epi-isositsirikine
  • (16R,19E)-19,20-Didehydro-17-hydroxycorynan-16-carboxylic acid methyl ester
  • Isositsirikine
  • (16R)-E-Isositsirikine
  • NSC 282700
  • NSC 338932
  • Rhazimanine
  • Indolo[2,3-a]quinolizine-2-acetic acid, 3-ethylidene-1,2,3,4,6,7,12,12b-octahydro-α-(hydroxymethyl)-, methyl ester, (αR,2R,3E,12bS)-
CAS:
6519-27-3
MF:
C21H26N2O3
MW:
354.45
Mol File:
6519-27-3.mol
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16-epi-isositsirikine Chemical Properties

Melting point:
263.5℃
Boiling point:
558.9±50.0 °C(Predicted)
Density 
1.26±0.1 g/cm3(Predicted)
pka
14.29±0.10(Predicted)
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16-epi-isositsirikine Usage And Synthesis

Description

An amorphous alkaloid found in Vinca rosea L., this laevorotatory base has [α]25D - 20° (CHCI3). In EtOH, the ultraviolet spectrum has absorption maxima at 224, 283 and 291 m/J.. The alkaloid forms a hemisulphate, m.p. 263.5°C and an amorphous O-acetate. The picrate is obtained in the form of brilliant yellow needles when crystallized from MeOH, m.p. 216°C.

Definition

ChEBI: 16R,19E-isositsirikine is an alkaloid. It has a role as a metabolite.

References

Kutney, Brown., Tetrahedron, 22,321 (1966)

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