ChemicalBook > Product Catalog > Chemical Reagents > Organic reagents > Aromatic acids > 5-Nitrosalicylic acid
5-Nitrosalicylic acid
5-Nitrosalicylic acid Basic information
- Product Name:
- 5-Nitrosalicylic acid
- Synonyms:
-
- 2-hydroxy-5-nitro-benzoicaci
- AURORA KA-2534
- ANILOTIC ACID
- 2-HYDROXY-5-NITROBENZOIC ACID
- RARECHEM AL BE 0192
- TIMTEC-BB SBB006535
- 5-NITROSALICYLIC ACID
- 5-NITRO-2-HYDROXY-BENZOIC ACID
- CAS:
- 96-97-9
- MF:
- C7H5NO5
- MW:
- 183.12
- EINECS:
- 202-548-8
- Product Categories:
-
- C7
- Carbonyl Compounds
- Organic acids
- API intermediates
- Carboxylic Acids
- Phenyls & Phenyl-Het
- FINE Chemical & INTERMEDIATES
- Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
- Mol File:
- 96-97-9.mol
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5-Nitrosalicylic acid Chemical Properties
- Melting point:
- 228-230 °C(lit.)
- Boiling point:
- 316.77°C (rough estimate)
- Density
- 1,65 g/cm3
- vapor pressure
- 0Pa at 25℃
- refractive index
- 1.6280 (estimate)
- storage temp.
- no restrictions.
- solubility
- water: soluble1g in 1475ml(lit.)
- form
- Liquid
- pka
- pK1:2.12 (25°C)
- color
- Clear yellow-beige to orange-brown
- Water Solubility
- Soluble in water 1g/1475ml .
- Merck
- 14,6631
- BRN
- 2213719
- InChIKey
- PPDRLQLKHRZIJC-UHFFFAOYSA-N
- LogP
- 1.158 at 25℃
- CAS DataBase Reference
- 96-97-9(CAS DataBase Reference)
- EPA Substance Registry System
- Benzoic acid, 2-hydroxy-5-nitro- (96-97-9)
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Safety Information
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-37/39
- WGK Germany
- 3
- Hazard Note
- Irritant
- TSCA
- Yes
- HS Code
- 29182990
MSDS
- Language:English Provider:2-Hydroxy-5-nitrobenzoic acid
- Language:English Provider:ACROS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ALFA
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5-Nitrosalicylic acid Usage And Synthesis
Chemical Properties
yellow powder
Uses
5-Nitrosalicylic Acid is a salicylic acid derivative with anti-inflammatory effect against colitis.
Definition
ChEBI: A monohydroxybenzoic acid in which the hydroxy group is ortho- to the carboxylic acid group and which has a nitro substituent para- to the phenolic hydroxy group.
Synthesis Reference(s)
Tetrahedron Letters, 36, p. 2377, 1995 DOI: 10.1016/0040-4039(95)00281-G
General Description
2-Hydroxy-5-nitrobenzoic acid inhibits the activity of wild type-bovine low Mr protein tyrosine phosphatase. The inhibition constant has been evaluated.
Flammability and Explosibility
Non flammable
Purification Methods
Crystallise the acid from Me2CO (charcoal), then twice more from Me2CO alone, aqueous EtOH (m 234-236o) or H2O (m 232-233o). [Beilstein 10 III 197, 10 IV 255.]
5-Nitrosalicylic acid Preparation Products And Raw materials
Preparation Products
5-Nitrosalicylic acidSupplier
Shanghai Taijilin Industrial Co., Ltd. Gold
- Tel
- 021-021-50630626 18964684208
- kate@tajilin.com
Shandong Yizhi Medical Technology Co., LTD Gold
- Tel
- 13287715206 15508629772
- 2786175817@qq.com
Weifang Boteng Chemical Co.,Ltd Gold
- Tel
- 18663610456
- 2858994498@qq.com
Henan Vcommend Consultrading Co., Ltd. Gold
- Tel
- 13393721940; 13393721940
- sales@vcommend.com
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
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5-Nitrosalicylic acid(96-97-9)Related Product Information
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- CHLOROPHOSPHONAZO III
- Ethyl 2-(Chlorosulfonyl)acetate
- 3-NITROSALICYLIC ACID 98+%,3-NITROSALICYLIC ACID
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